Table 4 Odds ratios for presence of anti-CCP2, RF autoantibodies, and anti-CarP according to smoking status

  N (total)

292

167

108

107

 Smoking ever, n (%)

179 (61.3)

97 (58.0)

67 (62.0)

89 (83.2)

 Smoking never, n (%)

113 (38.7)

70 (41.9)

41 (38.0)

18 (16.8)

 OR (95% CI)

1 (reference)

0.87 (0.59–1.29)

1.03 (0.65–1.63)

3.12 (1.79–5.46)*

  p value

–

0.50

0.89

<0.001*

  N (total)

242

129

128

270

 Smoking ever, n (%)

113 (46.7)

67 (51.9)

70 (54.7)

165 (61.1)

 Smoking never, n (%)

129 (53.3)

62 (48.1)

58 (45.3)

105 (38.9)

 OR (95% CI)

1 (reference)

1.23 (0.80–1.89)

1.38 (0.90–2.12)

1.79 (1.26–2.55)*

  p value

–

0.34

0.14

0.001*

  N (total)

263

110

193

229

 Smoking ever, n (%)

138 (52.5)

58 (52.7)

121 (62.7)

154 (67.2)

 Smoking never, n (%)

125 (47.5)

52 (47.3)

72 (37.3)

75 (32.8)

 OR (95% CI)

1 (reference)

1.01 (0.65–1.58)

1.52 (1.04–2.22)*

1.86 (1.29–2.69)*

  p value

–

0.96

0.03*

0.001*