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Table 3 Comparison of the changes in disease activity scores and biomarkers levels within 6 months in the axSpA groups with and without exercise intervention

From: Clinical improvement and reduction in serum calprotectin levels after an intensive exercise programme for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis

  All axSpA nr-axSpA AS
Exercise group (n = 40) Without exercise (n = 29) P value Exercise group (n = 18) Without exercise (n = 15) P value Exercise group (n = 22) Without exercise (n = 14) P value
∆ ASDAS-CRP -0.26 (0.58) -0.13 (0.77) <0.05 -0.29 (0.44) 0.03 (0.84) ns -0.24 (0.68) -0.13 (0.72) ns
∆ BASDAI -0.49 (1.40) 0.12 (1.40) <0.05 -0.70 (1.48) 0.42 (1.22) ns -0.32 (1.34) 0.12 (1.22) ns
∆ CRP -0.81 (4.67) -0.33 (9.70) ns 0.06 (1.94) 1.94 (12.20) ns -1.52 (6.02) -2.76 (5.49) ns
∆ Calprotectin -604.56 (1042.80) -149.28 (1255.70) <0.05 -599.42 (824.00) -190.33 (1180.60) ns -608.68 (1211.20) -149.28 (1255.70) ns
  1. Statistical analysis: the comparison of the mean of changes in all parameters was performed using the non-parametric Mann-Whitney U test. The multiple comparisons were corrected using Monte Carlo exact significance testing. All data are characterised as mean and (standard deviation). axSpA axial spondyloarthritis, nr-axSpA non-radiographic axial spondyloarthritis, AS ankylosing spondylitis, ASDAS-CRP AS disease activity score, CRP C-reactive protein, BASDAI Bath AS disease activity index, ∆ changes in the scores/biomarkers values, ns not significant