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Table 3 Comparison of the changes in disease activity scores and biomarkers levels within 6 months in the axSpA groups with and without exercise intervention

From: Clinical improvement and reduction in serum calprotectin levels after an intensive exercise programme for patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis

 

All axSpA

nr-axSpA

AS

Exercise group (n = 40)

Without exercise (n = 29)

P value

Exercise group (n = 18)

Without exercise (n = 15)

P value

Exercise group (n = 22)

Without exercise (n = 14)

P value

∆ ASDAS-CRP

-0.26 (0.58)

-0.13 (0.77)

<0.05

-0.29 (0.44)

0.03 (0.84)

ns

-0.24 (0.68)

-0.13 (0.72)

ns

∆ BASDAI

-0.49 (1.40)

0.12 (1.40)

<0.05

-0.70 (1.48)

0.42 (1.22)

ns

-0.32 (1.34)

0.12 (1.22)

ns

∆ CRP

-0.81 (4.67)

-0.33 (9.70)

ns

0.06 (1.94)

1.94 (12.20)

ns

-1.52 (6.02)

-2.76 (5.49)

ns

∆ Calprotectin

-604.56 (1042.80)

-149.28 (1255.70)

<0.05

-599.42 (824.00)

-190.33 (1180.60)

ns

-608.68 (1211.20)

-149.28 (1255.70)

ns

  1. Statistical analysis: the comparison of the mean of changes in all parameters was performed using the non-parametric Mann-Whitney U test. The multiple comparisons were corrected using Monte Carlo exact significance testing. All data are characterised as mean and (standard deviation). axSpA axial spondyloarthritis, nr-axSpA non-radiographic axial spondyloarthritis, AS ankylosing spondylitis, ASDAS-CRP AS disease activity score, CRP C-reactive protein, BASDAI Bath AS disease activity index, ∆ changes in the scores/biomarkers values, ns not significant