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Table 1 Demographics and baseline variables

From: Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data

 

ERAN

BSRBR

TNF inhibitor

Non-biologic

Total subjects

828

9905

2581

Age, years

57 (14)

56 (12)

60 (12)

Female sex

67%

76%

73%

BMI, kg/m2

27.6 (5.3)

27.0 (7.3)

27.4 (6.7)

Smoking status

 Never

39%

40%

38%

 Ex-smoker

25%

38%

41%

 Current

36%

22%

21%

 Duration, years

0.7 (0.6)

13 (10)

10 (10)

Positive serology

60%

65%

57%

1987 ACR criteria, yes

53%

100%

100%

DAS28-ESR

4.7 (1.5)

6.6 (1.0)

5.1 (1.3)

ESR, mm/h

30 (24)

46 (29)

34 (24)

SJC, 0–28

6 (5)

11 (6)

6 (5)

TJC, 0–28

7 (7)

16 (7)

8 (7)

VAS, 0–100

44 (25)

72 (20)

54 (24)

HAQ, 0–3

1.1 (0.8)

2.0 (0.6)

1.5 (0.8)

SF-36

 Physical function

30 (15)

16 (11)

24 (11)

 Bodily pain

33 (11)

25 (7)

31 (9)

 Vitality

42 (11)

33 (10)

39 (10)

 Mental health

46 (11)

40 (11)

45 (11)

 PCS

29 (12)

16 (8)

24 (11)

 MCS

47 (12)

44 (11)

48 (11)

DMARD by 6-month follow-up

91%

100%

100%

First recorded DMARD

 MTX monotherapy

48%

40%

0%

 SSZ monotherapy

31%

14%

0%

 MTX combination

12%

25%

0%

 Biologic

0%

0%

100%

  1. Baseline variables of the complete cases for the cohorts. Mean (SD) or percentage data are presented
  2. Abbreviations: ACR American College of Rheumatology, BSRBR British Society for Rheumatology Biologics Registers, DAS28 28-joint Disease Activity Score, DMARD Disease-modifying anti-rheumatic drug, ERAN Early Rheumatoid Arthritis Network, ESR Erythrocyte sedimentation rate, HAQ Health Assessment Questionnaire, SF-36 36-item Short Form Health Survey, SJC Swollen joint count, TJC Tender joint count, TNF Tumour necrosis factor, VAS Visual analogue scale, PCS Short Form Health Survey physical component score, MCS Short Form Health Survey mental component score, MTX methotrexate, SSZ sulphasalazine