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Table 1 Demographics and baseline variables

From: Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data

  ERAN BSRBR
TNF inhibitor Non-biologic
Total subjects 828 9905 2581
Age, years 57 (14) 56 (12) 60 (12)
Female sex 67% 76% 73%
BMI, kg/m2 27.6 (5.3) 27.0 (7.3) 27.4 (6.7)
Smoking status
 Never 39% 40% 38%
 Ex-smoker 25% 38% 41%
 Current 36% 22% 21%
 Duration, years 0.7 (0.6) 13 (10) 10 (10)
Positive serology 60% 65% 57%
1987 ACR criteria, yes 53% 100% 100%
DAS28-ESR 4.7 (1.5) 6.6 (1.0) 5.1 (1.3)
ESR, mm/h 30 (24) 46 (29) 34 (24)
SJC, 0–28 6 (5) 11 (6) 6 (5)
TJC, 0–28 7 (7) 16 (7) 8 (7)
VAS, 0–100 44 (25) 72 (20) 54 (24)
HAQ, 0–3 1.1 (0.8) 2.0 (0.6) 1.5 (0.8)
SF-36
 Physical function 30 (15) 16 (11) 24 (11)
 Bodily pain 33 (11) 25 (7) 31 (9)
 Vitality 42 (11) 33 (10) 39 (10)
 Mental health 46 (11) 40 (11) 45 (11)
 PCS 29 (12) 16 (8) 24 (11)
 MCS 47 (12) 44 (11) 48 (11)
DMARD by 6-month follow-up 91% 100% 100%
First recorded DMARD
 MTX monotherapy 48% 40% 0%
 SSZ monotherapy 31% 14% 0%
 MTX combination 12% 25% 0%
 Biologic 0% 0% 100%
  1. Baseline variables of the complete cases for the cohorts. Mean (SD) or percentage data are presented
  2. Abbreviations: ACR American College of Rheumatology, BSRBR British Society for Rheumatology Biologics Registers, DAS28 28-joint Disease Activity Score, DMARD Disease-modifying anti-rheumatic drug, ERAN Early Rheumatoid Arthritis Network, ESR Erythrocyte sedimentation rate, HAQ Health Assessment Questionnaire, SF-36 36-item Short Form Health Survey, SJC Swollen joint count, TJC Tender joint count, TNF Tumour necrosis factor, VAS Visual analogue scale, PCS Short Form Health Survey physical component score, MCS Short Form Health Survey mental component score, MTX methotrexate, SSZ sulphasalazine