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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Immune reconstitution 20 years after treatment with alemtuzumab in a rheumatoid arthritis cohort: implications for lymphocyte depleting therapies

Fig. 2

a Circulating levels of serum IFN-γ and IL-15 (pg/ml) in the alemtuzumab cohort and controls. We show a significant increase in IFN-γ (p < 0.0001) and IL-15 (p = 0.0188) in the alemtuzumab cohort. b, c CD4+ total memory and central memory T cells (cell number × 109/L) demonstrated significant inverse associations with serum IL-15 (pg/ml) (p = 0.034, r 2 = 0.286 and p = 0.037, r 2 = 0.274 respectively). Results were considered significant when the p value was <0.05. *p < 0.05, ***p < 0.0001

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