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Table 2 Demographic, clinical, and laboratory characteristics of patients in the TAK >40 and TAK ≤40 groups who fulfilled at least three criteria, excluding the age criterion

From: Fewer subsequent relapses and lower levels of IL-17 in Takayasu arteritis developed after the age of 40 years

Variable TAK >40, n = 20 TAK ≤40 who fulfilled at least three criteria, excluding the age criterion, n = 14 P value
Onset age, years (IQR) 56 (48–62) 23 (20–29)  
Female, n (%) 19 (95) 13 (93) 1.00
HLA-B52, n (%) 7 (47) , n = 15 10 (83), n = 12 0.107
BMI, kg/m2 (IQR) 21.9 (20.2–26.2) 21.2 (18.6–22.2) 0.48
Family history 1 (5) 0 (0) 1.00
Smoking 5 (25) 3 (21) 1.00
Complication, n (%)
 DM 2 (10) 1 (7) 1.00
 CKD 0 (0) 1 (7) 0.41
 IBD 1 (5) 1 (7) 1.00
 PG 1 (5) 1 (7) 1.00
Angiographic classification, n (%)
 Type I 5 (25) 5 (36) 0.70
 Type IIa 2 (10) 3 (21) 0.63
 Type IIb 3 (15) 2 (14) 1.00
 Type IV 1 (5) 0 (0) 1.00
 Type V 9 (45) 4 (29) 0.48
Fever 11 (55) 10 (71) 0.48
Malaise 10 (50) 8 (57) 0.74
Headache 5 (25) 9 (64) 0.035*
Dizziness 0 (0) 4 (29) 0.022*
Orthostatic hypotension 2 (10) 8 (43) 0.006*
Ophthalmic symptoms 1 (5) 4 (29) 0.135
Carotid bruit 7 (35) 10 (71) 0.080
Cervical pain 4 (20) 4 (29) 0.69
Discrepancy in blood pressure 10 (50) 10 (71) 0.30
Upper limb pain 4 (20) 8 (57) 0.036*
Pulselessness 4 (20) 6 (43) 0.25
Chest pain 0 (0) 4 (29) 0.022*
Abdominal bruit 6 (30) 4 (29) 1.00
Arthralgia 5 (25) 3 (21) 1.00
Aortic valve regurgitation 5 (25) 7 (50) 0.16
WBC, ×103/μL (normal range 3.5–9.8) (IQR) 9.4 (7.1–11.7), n = 20 9.9 (7.1–14.3), n = 14 0.66
Hb, g/dL (normal range11.3–17.6) (IQR) 12.4 (10.1–13.2), n = 20 10.8 (8.8–11.7), n = 14 0.033*
Plt × 104/μL, (normal range 13.0–36.9) (IQR) 29.3 (23.4–38.2), n = 20 36.9 (24.2–51.7), n = 14 0.26
CRP, mg/dL (normal range <0.14) (IQR) 4.2 (0.5–9.0), n = 20 7.0 (0.9–10.0), n = 14 0.46
ESR, mm/h, (normal range <15) (IQR) 75 (32–91), n = 18 75 (50–88), n = 10 0.85
Alb, g/dL, (normal range 3.8–5.2) (IQR) 3.7 (3.1–4.1), n = 19 3.7 (3.1–4.4), n = 13 0.95
IgG, mg/dL, (normal range 870–1700) (IQR) 1410 (1100–1670), n = 17 1660 (1170–2250), n = 14 0.34
  1. TAK >40 Takayasu arteritis onset after age 40 years; TAK ≤40 TAK onset age 40 years or younger, BMI body mass index, DM diabetes mellitus, CKD chronic kidney disease, IBD inflammatory bowel diseases, PG pyoderma gangrenosum, WBC white blood cell count, Hb hemoglobin, Plt platelet, CRP C reactive protein, ESR erythrocyte sedimentation rate, Alb albumin, IgG immunoglobulin. *P < 0.05