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Table 6 WORMS scoring of MRI of the knee at each visit

From: Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint

WORMS 25 M 50 M P1 P value 75 M 150 M P2 P value
Baseline 67.0 (19.8) 78.8 (40.9) 76.5 (23.5) 71.3 (21.4) 62.0 (17.9) 70.8 (14.7)
6 months 67.5 (20.5) 77.9 (41.2) 74.9 (22.4) 0.5521 71.4 (20.9) 62.0 (17.7) 69.9 (14.3) 0.7360
12 months 66.1 (19.2) 78.0 (41.1) 74.9 (22.5) 0.5310 67.0 (20.9) 60.6 (15.7) 72.3 (15.2) 0.0609
  1. Values are shown as mean (SD)
  2. The range of WORMS score used in this study was 0–314
  3. 25 M, 50 M, 75 M, 150 M = 25, 50, 75, 150 million cells, respectively
  4. P1, P2 = Placebo 1 and 2, respectively
  5. MRI magnetic resonance imaging, WORMS whole-organ magnetic resonance imaging score