Skip to main content

Table 1 Demographic and clinical characteristics of study subjects with synovial fluid analyzed by Luminex assay and gene expression

From: Differential gene and protein expression of chemokines and cytokines in synovial fluid of patients with arthritis

 

PsA

OA

Gout

RA

p Valuea

Luminex (n = 40)

mRNA (n = 30)

Luminex (n = 14)

mRNA (n = 4)

Luminex (n = 8)

mRNA (n = 6)

Luminex (n = 11)

mRNA (n = 5)

Male sex

26 (65%)

18 (60%)

3 (25%)

0 (0%)

7 (87.5%)

5 (83.3%)

2 (20%)

0 (0%)

0.0003

Age, yearsb

44.4 (12.9)

45.1 (13.3)

69.1 (11.4)

79.0 (1.4)

61.3 (22.0)

56.5 (23.8)

49.0 (17.5)

52.3 (17.8)

<0.0001

Duration of psoriasisc

14 (7.3–21.8)

18 (10–24)

–

–

–

–

–

–

0.584

Duration of PsAc

9 (3–15)

10 (3–15)

–

–

–

–

–

–

0.755

PASIc

1.8 (0.6–4.2)

1.8 (0.6–4.5)

–

–

–

–

–

–

0.959

Number of swollen jointsc,d

2 (1–3)

1 (1–3)

–

–

–

–

–

–

0.834

Number of tender jointsc,d

2 (0–5)

1 (0–3.8)

–

–

–

–

–

–

0.435

Current use of NSAIDs

18 (45%)

12 (40%)

–

–

–

–

–

–

0.676

Current use of DMARDs

17 (43%)

14 (47%)

–

–

–

–

–

–

0.728

Current use of biologics

10 (25%)

9 (30%)

–

–

–

–

–

–

0.642

  1. Abbreviations: DMARD Disease-modifying antirheumatic drug, mRNA Messenger RNA, NSAID Nonsteroidal anti-inflammatory drug, OA Osteoarthritis, PASI Psoriasis Area Severity Index, PsA Psoriatic arthritis, RA Rheumatoid arthritis
  2. aOne-way analysis of variance or Mann-Whitney U test (continuous variables) or Pearson’s chi-square test (categorical variables)
  3. bMean (SD)
  4. cMedian (interquartile range)
  5. dTender joints were determined clinically in 68 joints, swollen joints in 66 (excluding hips)