Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 2 Changes in ultrasound measures of synovial thickening and synovial vascularity in treatment responders and non-responders during 12 weeks of anti-TNF treatment

From: Increase in circulating Th17 cells during anti-TNF therapy is associated with ultrasonographic improvement of synovitis in rheumatoid arthritis

Parameter Baseline Week 1 Week 4 Week 12
  Median (range) Median (range) P value Median (range) P value Median (range) P value
Total synovial thickness area score (10 MCP trans STA)
Responders (n = 16) 203,039 (134,989–311,455) 186,048 (143,073–281,634) ns 181,288 (115,760–257,808) * 139,824 (94,708–226,389) **
Non-responders (n = 9) 110,231 (98,185–156,452) 125,946 (114,966–180,770) ns 117,202 (94,965–220,584) ns 116,119 (67,559–189,271) ns
Total synovial power Doppler area score (10 MCP trans PDA)
Responders (n = 16) 3213 (115–6772) 949 (156–2967) * 114 (17–2310) ** 76 (4.5–1075) *
Non-responders (n = 9) 25 (0–1079) 48 (0–98) ns 57 (0–169) ns 87 (12.5 − 780) ns
  1. Values are presented as median (interquartile range). Comparison of each time point on treatment versus baseline made using Wilcoxon matched pairs test; *p < 0.05, **p < 0.005, ns non-significant