Table 2 Changes in ultrasound measures of synovial thickening and synovial vascularity in treatment responders and non-responders during 12Â weeks of anti-TNF treatment
Parameter | Baseline | Week 1 | Week 4 | Week 12 | |||
|---|---|---|---|---|---|---|---|
| Â | Median (range) | Median (range) | P value | Median (range) | P value | Median (range) | P value |
Total synovial thickness area score (10 MCP trans STA) | |||||||
Responders (n = 16) | 203,039 (134,989–311,455) | 186,048 (143,073–281,634) | ns | 181,288 (115,760–257,808) | * | 139,824 (94,708–226,389) | ** |
Non-responders (n = 9) | 110,231 (98,185–156,452) | 125,946 (114,966–180,770) | ns | 117,202 (94,965–220,584) | ns | 116,119 (67,559–189,271) | ns |
Total synovial power Doppler area score (10 MCP trans PDA) | |||||||
Responders (n = 16) | 3213 (115–6772) | 949 (156–2967) | * | 114 (17–2310) | ** | 76 (4.5–1075) | * |
Non-responders (n = 9) | 25 (0–1079) | 48 (0–98) | ns | 57 (0–169) | ns | 87 (12.5 − 780) | ns |