TY - JOUR AU - Volkmann, Elizabeth R. AU - Tashkin, Donald P. AU - Roth, Michael D. AU - Clements, Philip J. AU - Khanna, Dinesh AU - Furst, Daniel E. AU - Mayes, Maureen AU - Charles, Julio AU - Tseng, Chi-Hong AU - Elashoff, Robert M. AU - Assassi, Shervin PY - 2016 DA - 2016/12/30 TI - Changes in plasma CXCL4 levels are associated with improvements in lung function in patients receiving immunosuppressive therapy for systemic sclerosis-related interstitial lung disease JO - Arthritis Research & Therapy SP - 305 VL - 18 IS - 1 AB - Increased circulatory levels of the chemokine CXCL4 have been associated with the presence of interstitial lung disease (ILD) in an observational study of patients with systemic sclerosis (SSc). The purpose of the present study was to evaluate the relationship between baseline CXCL4 level and extent of ILD in the context of a randomized controlled trial and to determine whether changes in CXCL4 levels in response to immunosuppression are associated with future progression of SSc-ILD. SN - 1478-6362 UR - https://doi.org/10.1186/s13075-016-1203-y DO - 10.1186/s13075-016-1203-y ID - Volkmann2016 ER -