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Table 6 Time-lag model: multivariate analysis, extended model

From: The relationship between synovitis quantified by an ultrasound 7-joint inflammation score and physical disability in rheumatoid arthritis – a cohort study

Predictor

Model without US-7

Model with US-7

β (95% CI)

P value

β (95% CI)

P value

Female

0.182 (-0.007; 0.370)

0.059

0.167 (-0.012; 0.347)

0.068

Age (years)

0.172 (0.113; 0.231)

<0.001

0.169 (0.113; 0.226)

<0.001

BMI

0.009 (-0.009; 0.026)

0.316

0.007 (-0.010; 0.024)

0.405

RF+ or ACPA+

0.060 (-0.103; 0.224)

0.471

0.052 (-0.106; 0.210)

0.517

Prevalent vs. incident RA

0.026 (-0.156; 0.209)

0.779

0.010 (-0.165; 0.186)

0.910

Previous DAS28-CRP

0.100 (0.061; 0.140)

<0.001

0.161 (0.113; 0.208)

<0.001

Previous GSsynSS

 

-0.004 (-0.019; 0.010)

0.563

Previous PDsynSS

 

-0.021 (-0.040; -0.002)

0.035

Previous GStenSS

 

0.000 (-0.085; 0.085)

0.997

Previous PDtenSS

 

-0.015 (-0.078; 0.048)

0.643

Previous erosions score

 

0.012 (-0.022; 0.046)

0.484

R 2 (% variability explained)

32.3

39.1

Improved R 2

 

6.8

<0.001 *

  1. Predicted variable is current health assessment questionnaire (HAQ) score. Comparison of models based on baseline demographic, anthropometric and immunological parameters, and previous disease activity score in 28 joints (DAS28) with or without previous German 7-joint ultrasound score (US7) sum-scores (SS) (previous = measured 12 months ago). *P value of significance for improvement of prediction. RA rheumatoid arthritis, BMI body mass index, RF rheumatoid factor, ACPA anti-citrullinated peptide antibodies, GS greyscale, PD power Doppler, syn synovitis, ten tenosynovitis. P-values higlighted in italics are significant at p < 0.05