Table 2 Predictors for first ULT dispensation within 365 days after diagnosis

Male (ref)

30.33

Female

26.39

0.87 (0.79–0.95)

0.87 (0.79–0.97)

0.86(0.78–0 .94)

 20–49 (ref)

22.84

 50–59

23.21

1.03 (0.87–1.22)

0.90 (0.72–1.12)

0.96 (0.81–1.14)

 60–69

30.14

1.38 (1.19–1.59)

0.90 (0.74–1.10)

1.15 (0.99–1.34)

 70–79

34.19

1.61 (1.40–1.86)

0.82 (0.67–1.00)

1.25 (1.07–1.46)

 80–

30.74

1.46 (1.26–1.69)

0.57 (0.46–0.71)

1.03 (0.87–1.21)

 ≤9 years (ref)

31.10

 10–12 years

28.78

0.92(0.83–1.31)

 >12 years

26.32

0.83(0.73–0.93)

 0 (ref)

23.53

 1–2

34.20

1.57 (1.44–1.72)

1.29 (1.15–1.45)

1.45 (1.31–1.60)

 >2

38.79

1.91 (1.69–2.15)

1.43 (1.23–1.66)

1.73 (1.51–1.99)

0 (ref)

27.48

1

40.75

1.67 (1.50–1.87)

1.47 (1.31–1.64)

eGFR >60 mL/min/1.73 m² “normal kidney function” (ref)

26.56

eGFR 60–31 mL/min/1.73 m² “reduced kidney function”

44.33

1.91 (1.73–2.11)

2.11 (1.88–2.37)

eGFR 30–10 mL/min/1.73 m^{2 “}severely reduced kidney function”

44.71

2.01 (1.67–2.41)

2.31 (1.90–2.82)

eGFR <10 mL/min/1.73 m² “end-stage kidney failure”

30.77

1.14 (0.43–3.04)

1.17 (0.44–3.12)

2011, ref

2012

1.10 (0.99–1.21)

2013

1.02 (0.92–1.13)