Fig. 4From: Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapyLongitudinal change in serum concentrations of IL-6 (a) and IL-18 (b) after treatment with canakinumab. Data are shown for trial 2. Similar results were observed for plasma samples in trial 1 (data available until day 29; not shown). The left panel (b) shows all data; the right panel represents a magnification of the lower portion of the y-axis. IL-6 interleukin-6, IL-18 interleukin 18Back to article page