Table 1 Baseline characteristics and the correlations with serum soluble CD163 levels in patients with polymyositis/dermatomyositis-related interstitial lung disease
Variables | Patients (n = 48) | r | P value |
|---|---|---|---|
Age at the ILD diagnosis (years) | 55, 32–76 | −0.05 | 0.72 |
Male | 17 (35%) | − | − |
Current or former smoker | 20 (42%) | − | − |
CADM/classic DM/PM | 21 (44%)/24 (50%)/3 (6%) | − | − |
Fever | 20 (42%) | − | − |
Cough | 20 (42%) | − | − |
Dyspnea | 23 (48%) | − | − |
Muscle pain or weakness | 27 (56%) | − | − |
Rash typical of DM | 45 (94%) | − | − |
Raynaud’s phenomenon | 5 (10%) | − | − |
Arthralgia | 17 (35%) | − | − |
CK (IU/mL) | 162, 24–5274 | 0.24 | 0.10 |
CRP (mg/dL) | 0.36, 0.03–8.33 | 0.32 | 0.03 |
KL-6 (U/mL) | 883, 249–4323 | 0.14 | 0.33 |
Ferritin (ng/mL) | 116.5, 14–12701 | 0.25 | 0.08 |
PaO2 on room air (Torr) | 75.3, 47.9–109.0 | −0.16 | 0.28 |
Anti-MDA5-positive/anti-ARS positive/others | 14 (29%)/19 (40%)/15 (31%) | − | − |
Predicted FVC (%) | 65.8, 40.6–107.7 (n = 45) | −0.30 | 0.045 |
Predicted DLco (%) | 60.3, 27.4–127.2 (n = 18) | −0.15 | 0.55 |
BAL-lymphocytes (%) | 7.2, 1.2–70.0 (n = 35) | 0.03 | 0.85 |