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Table 3 Serum levels of inflammatory cytokines at baseline in patients with rheumatoid arthritis (RA) and healthy volunteers

From: CD14brightCD16+ intermediate monocytes are induced by interleukin-10 and positively correlate with disease activity in rheumatoid arthritis

  RA (n = 35) HV (n = 14) p value
GM-CSF 0.089 (0–0.28) 0 (0–0.45) 0.37
IFN-γ 1.31 (0.87–2.04) 1.17 (0.80–3.19) 0.68
IL-1β 0.027 (0–0.12) 0 (0–0.18) 0.74
IL-10 1.39 (0.98–2.16) 0.95 (0.55–1.29) 0.017
IL-12 0.70 (0.38–1.06) 0.53 (0.21–0.99) 0.21
IL-2 0.19 (0.046–0.30) 0.13 (0–0.22) 0.16
IL-6 3.19 (1.36–6.95) 0.51 (0.35–1.09) 0.0005
IL-8 13.77 (10.81–20.53) 10.90 (5.44–14.21) 0.019
TNF-α 3.75 (2.55–4.61) 3.48 (2.70–4.58) 0.99
M-CSF 164.84 (107.93–266.70) 157.82 (141.32–194.77) 0.82
  1. Data presented as median in pg/mL (interquartile range). HV healthy volunteers, GM-CSF granulocyte-macrophage colony-stimulating factor, IFN-γ interferon-γ, M-CSF macrophage colony-stimulating factor. Statistical analysis, Wilcoxon rank sum test