| |
RA (n = 35)
|
HV (n = 14)
|
p value
|
|---|
|
GM-CSF
|
0.089 (0–0.28)
|
0 (0–0.45)
|
0.37
|
|
IFN-γ
|
1.31 (0.87–2.04)
|
1.17 (0.80–3.19)
|
0.68
|
|
IL-1β
|
0.027 (0–0.12)
|
0 (0–0.18)
|
0.74
|
|
IL-10
|
1.39 (0.98–2.16)
|
0.95 (0.55–1.29)
|
0.017
|
|
IL-12
|
0.70 (0.38–1.06)
|
0.53 (0.21–0.99)
|
0.21
|
|
IL-2
|
0.19 (0.046–0.30)
|
0.13 (0–0.22)
|
0.16
|
|
IL-6
|
3.19 (1.36–6.95)
|
0.51 (0.35–1.09)
|
0.0005
|
|
IL-8
|
13.77 (10.81–20.53)
|
10.90 (5.44–14.21)
|
0.019
|
|
TNF-α
|
3.75 (2.55–4.61)
|
3.48 (2.70–4.58)
|
0.99
|
|
M-CSF
|
164.84 (107.93–266.70)
|
157.82 (141.32–194.77)
|
0.82
|
- Data presented as median in pg/mL (interquartile range). HV healthy volunteers, GM-CSF granulocyte-macrophage colony-stimulating factor, IFN-γ interferon-γ, M-CSF macrophage colony-stimulating factor. Statistical analysis, Wilcoxon rank sum test
