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Table 3 Serum levels of inflammatory cytokines at baseline in patients with rheumatoid arthritis (RA) and healthy volunteers

From: CD14brightCD16+ intermediate monocytes are induced by interleukin-10 and positively correlate with disease activity in rheumatoid arthritis

 

RA (n = 35)

HV (n = 14)

p value

GM-CSF

0.089 (0–0.28)

0 (0–0.45)

0.37

IFN-γ

1.31 (0.87–2.04)

1.17 (0.80–3.19)

0.68

IL-1β

0.027 (0–0.12)

0 (0–0.18)

0.74

IL-10

1.39 (0.98–2.16)

0.95 (0.55–1.29)

0.017

IL-12

0.70 (0.38–1.06)

0.53 (0.21–0.99)

0.21

IL-2

0.19 (0.046–0.30)

0.13 (0–0.22)

0.16

IL-6

3.19 (1.36–6.95)

0.51 (0.35–1.09)

0.0005

IL-8

13.77 (10.81–20.53)

10.90 (5.44–14.21)

0.019

TNF-α

3.75 (2.55–4.61)

3.48 (2.70–4.58)

0.99

M-CSF

164.84 (107.93–266.70)

157.82 (141.32–194.77)

0.82

  1. Data presented as median in pg/mL (interquartile range). HV healthy volunteers, GM-CSF granulocyte-macrophage colony-stimulating factor, IFN-γ interferon-γ, M-CSF macrophage colony-stimulating factor. Statistical analysis, Wilcoxon rank sum test