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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis

Fig. 1

a Of the 377 genes associated with rheumatoid arthritis (RA) that were reported by Okada et al., 11 were uni-directionally differentially expressed in whole blood from both treated patients (tRA) and untreated patients (nRA) with RA, when compared to 12 healthy controls (HC). The p values from both analyses were combined by Fisher’s method. A significance threshold of p = 0.05 after correction for false discovery rate was applied. FPKM fragments per kilobase of transcript per million mapped reads. b Clustering on the 11-gene expression profile for grouping of individual samples using Jensen-Shannon distance (shown on axis Y)

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Arthritis Research & Therapy

ISSN: 1478-6362

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