Table 1 Patient characteristics at enrollment
Patient | Age (years) | Sex | Country of origin | Race | Relevant prior treatment | Current treatment | Historical disease features | Age at ulcer onset (years) | Primary outcome |
|---|---|---|---|---|---|---|---|---|---|
1 | 59 | F | USA | Caucasian | Abatacept Adalimumab Azathioprine Colchicine Glucocorticoids Infliximab | Azathioprine | Oral and genital ulcers, GI ulcers, skin pustules, arthralgias | 7 | Treatment failure |
2 | 19 | F | USA | Caucasian | Colchicine Glucocorticoids Sulfasalazine | Colchicine Sulfasalazine Prednisone (15 mg/day) | Oral and genital ulcers, GI ulcers, thrombophlebitis, arthralgias, skin pustules, folliculitis, pathergy, HLA-B51-positive | 16 | Complete response |
3 | 40 | F | USA | Mixed | Colchicine, Hydroxychloroquine Glucocorticoids | Colchicine Hydroxychloroquine | Oral and genital ulcers, skin pustules, arthritis | 38 | Partial response |
4 | 30 | F | USA | Caucasian | Colchicine Glucocorticoids | None | Oral and genital ulcers, skin pustules, anterior uveitis, arthritis | 2 | Complete response |
5 | 26 | F | USA | Caucasian | Azathioprine Glucocorticoids | Azathioprine | Oral and genital ulcers, GI ulcers, skin pustules, deep vein thrombosis | 21 | Treatment failure |
6 | 36 | M | Ethiopia | African | Colchicine Glucocorticoids | Prednisone (20 mg/day) | Oral and genital ulcers, skin pustules, panuveitis, arthritis | 31 | Partial response |