Fig. 7

S100A8 primes human macrophages for BCP-induced IL-1β production. Human macrophages were primed with recombinant human S100A8 (1 μg/ml) for 3 h prior to stimulation with BCP for 6 h. Cell supernatants were assessed for IL-1β, IL-1α, and TNF-α by ELISA. Results indicate mean (± SEM) of three independent experiments. ***P ≤ 0.001