| |
ADMA
|
SDMA
|
ADMA:SDMA
|
|---|
|
Factor
|
Main Eff.
|
Inflam.
|
Int.
|
Main Eff.
|
Inflam.
|
Int.
|
Main Eff.
|
Inflam.
|
Int.
|
|---|
|
Log2ACh
|
0.390
|
0.954
|
0.636
|
0.008
|
0.030
|
0.014
|
0.007
|
0.093
|
0.027
|
|
Log2SNP
|
0.702
|
0.989
|
0.824
|
0.074
|
0.056
|
0.042
|
0.100
|
0.151
|
0.087
|
|
Log2FMD
|
0.363
|
0.767
|
0.677
|
0.420
|
0.097
|
0.092
|
0.174
|
0.138
|
0.110
|
|
Log2GTN
|
0.754
|
0.702
|
0.823
|
0.799
|
0.812
|
0.868
|
0.959
|
0.607
|
0.737
|
|
Log2cIMT
|
0.217
|
0.323
|
0.051
|
0.550
|
0.265
|
0.562
|
0.607
|
0.953
|
0.259
|
|
Log2SEVR
|
0.876
|
0.727
|
0.706
|
0.006
|
0.049
|
0.052
|
0.058
|
0.252
|
0.268
|
|
AIx (HR 75)
|
0.204
|
0.367
|
0.246
|
0.205
|
0.221
|
0.127
|
0.050
|
0.097
|
0.036
|
-
p values from general linear models, with three terms included in each model: Main Eff. – the main effect of the factor being considered, Inflam. – a binary variable, stating whether a patient had high levels of inflammation (ESR > 25 and CRP > 5), Int. – an interaction term between Main Eff. and Inflam., testing whether the relationship between the factor and outcome differs by the degree of inflammation. Bold p values are significant at p < 0.05
-
ADMA asymmetric dimethylarginine, SDMA symmetric dimethylarginine, ACh acetylcholine, SNP sodium nitroprusside, FMD flow-mediated dilatation, GTN glyceryl-trinitrate mediated dilatation, cIMT intima media thickness, SEVR subendocardial viability ratio, AIx augmentation index, HR heart rate
