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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Proangiogenic effects of soluble α-Klotho on systemic sclerosis dermal microvascular endothelial cells

Fig. 1

Schematic representation of the molecular complex formed by vascular endothelial growth factor (VEGF)-bound VEGF receptor-2 (VEGFR-2), transient receptor potential canonical-1 (TRPC-1) and soluble α-Klotho (sKl) on the surface of endothelial cells (ECs). This molecular complex regulates the influx of Ca2+ and the permeability of the plasma membrane contributing to the maintenance of EC integrity

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Arthritis Research & Therapy

ISSN: 1478-6362

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