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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Excessive activation of the TLR9/TGF-β1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus

Fig. 1

Levels of Toll-like receptor 9 (TLR9), transforming growth factor-β1 (TGF-β1), and platelet-derived growth factor-B (PDGF-B) in the peripheral blood of systemic lupus erythematosus (SLE) patients. The mRNA expression of TLR9 (a) in the peripheral blood of SLE patients (N SLE = 112) and healthy controls (N Control = 49). Levels of TGF-β1 (b) and PDGF-B (c) in the plasma of SLE patients (N SLE = 77) and healthy controls (N Control = 56). Levels of SLE Disease Activity Index (SLEDAI) (d), TGF-β1 (e), and PDGF-B (f) in the same group of SLE patients (N SLE = 20) before and after immunosuppressive treatment. The results in a.b.c. are presented as Mean and SEM. GAPDH glyceraldehyde-3-phosphate dehydrogenase

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