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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Th17 and CD24hiCD27+ regulatory B lymphocytes are biomarkers of response to biologics in rheumatoid arthritis

Fig. 2

Baseline levels and evolution of lymphocyte subpopulations in patients with rheumatoid arthritis according to Disease Activity Score in 28 joints (DAS28) remission or European League Against Rheumatism (EULAR) response at month (M)6. a Baseline levels and evolution of CD24hiCD27+ B regulatory cells (Breg) in percentage between M0 and M6 in the patients who achieved DAS 28 remission (n = 7) or not (n = 19) at M6. b Initial levels and evolution of T regulatory cells (Treg) in percentage between M0 and M6 in the patients who achieved DAS28 remission (n = 7) or not (n = 19) at M6. c Initial levels and evolution of CD24hiCD27+ Breg in percentage between M0 and M6 in patients who achieved good EULAR response at M6 (n = 9) or not (n = 17). d Baseline levels and evolution of T helper 17 (Th17) cells in percentage between M0 and M6 in patients who achieved good EULAR response at M6 (n = 9) or not (n = 17). Results in box plots are median and IQR; difference observed between the two groups was assessed by the Mann–Whitney test at M0 and the general linear model (GLM) procedure and MIXED SAS for repetitive analyses. *p < 0.05, **p < 0.01

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