Table 4 Characteristics of patients with SSc by PAH status
| Â | PAH | No PAH | P value |
|---|---|---|---|
mean ± SD or % | mean ± SD or % | ||
Number of patients | 209 | 1283 | Â |
Age at recruitment, years | 63.1 ± 10.4 | 56.3 ± 12.7 | <0.001 |
Disease duration at recruitment, yearsa | 13.6 ± 11.5 | 10.4 ± 9.9 | <0.001 |
Female | 87.1% | 86.2% | 0.88 |
Limited disease subtype | 73.9% | 70.3% | 0.43 |
Anti-centromere pattern ANA | 52.6% | 44.1% | 0.02 |
Scl 70 positive | 6.9% | 15.2% | 0.003 |
RNA polymerase III positive | 14.4% | 12.9% | 0.65 |
Digital ulcers ever | 53.0% | 41.9% | 0.003 |
Telangiectasia ever | 91.4% | 82.4% | <0.001 |
Calcinosis ever | 53.3% | 34.7% | <0.001 |
Joint contractures ever | 45.8% | 35.7% | 0.007 |
GORD | 45.9% | 45.3% | 0.48 |
Bowel dysmotility | 27.3% | 22.7% | 0.15 |
Anal incontinence | 32.1% | 25.7% | 0.05 |
WHO Functional Class | |||
 Class I | 4 (2.1%) | 467(39.1%) | <0.001 |
 Class II | 25 (12.9%) | 469 (39.2%) | |
 Class III | 106 (54.9%) | 238 (19.9%) | |
 Class IV | 58(30.1%) | 22(1.8%) | |
NT-pro-BNP | 218.9 ± 285.7 | 75.1 ± 159.8 | 0.005 |