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Table 3 SLC2A9 and ABCG2 genotype frequency in Polynesian ancestry subsets according to tophus status

From: Population-specific association between ABCG2 variants and tophaceous disease in people with gout

  Eastern Polynesian ancestry Western Polynesian ancestry
With data, % No tophi (n = 291) Tophi (n = 173) p a With data, % No tophi (n = 221) Tophi (n = 166) p a
SLC2A9 rs11942223 protective allele (C) present, n (%) 100 24 (8.2%) 17 (9.8%) 0.56 100 12 (5.4%) 8 (4.8%) 0.79
ABCG2 rs2231142 risk allele (T) present, n (%) 100 70 (24.1%) 50 (28.9%) 0.25 100 150 (67.9%) 130 (78.3%) 0.023
ABCG2 rs10011796 risk allele (T) present, n (%) 98.3 242 (84.9%) 142 (83.0%) 0.60 98.2 185 (85.6%) 157 (95.7%) 0.001
  1. a P value from Pearson’s chi-squared test