Table 3 SLC2A9 and ABCG2 genotype frequency in Polynesian ancestry subsets according to tophus status
From: Population-specific association between ABCG2 variants and tophaceous disease in people with gout
Eastern Polynesian ancestry | Western Polynesian ancestry | |||||||
|---|---|---|---|---|---|---|---|---|
With data, % | No tophi (n = 291) | Tophi (n = 173) | p a | With data, % | No tophi (n = 221) | Tophi (n = 166) | p a | |
SLC2A9 rs11942223 protective allele (C) present, n (%) | 100 | 24 (8.2%) | 17 (9.8%) | 0.56 | 100 | 12 (5.4%) | 8 (4.8%) | 0.79 |
ABCG2 rs2231142 risk allele (T) present, n (%) | 100 | 70 (24.1%) | 50 (28.9%) | 0.25 | 100 | 150 (67.9%) | 130 (78.3%) | 0.023 |
ABCG2 rs10011796 risk allele (T) present, n (%) | 98.3 | 242 (84.9%) | 142 (83.0%) | 0.60 | 98.2 | 185 (85.6%) | 157 (95.7%) | 0.001 |