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Table 5 Immunologic markers at primary Sjögren’s syndrome diagnosis or later by smoking status at inclusion n (% of available)

From: Cigarette smoking and the risk of primary Sjögren’s syndrome: a nested case control study

  Current smoker P value* Former smoker P value* Never smoker P value*
Anti-SSApositive, n (%) 8 (80) 0.29 18 (56) 0.60 10 (56) 0.78
Anti- SSB positive, n (%) 7 (70) 0.07 11 (34) 0.43 6 (33) 0.57
ANA positive, n (%) 9 (90) 0.26 20 (63) 0.08 15 (83) 0.35
RF positive, n (%) 4 (44) 0.72 16 (50) 0.60 12 (67) 0.26
Autoantibodya negative 1 (10) 1.00 7 (22) 0.16 1 (6) 0.26
Positive lower lip biopsy, n (%) 8 (80) 0.63 23 (82) 0.71 15 (94) 0.41
  1. Smoking status at inclusion in the health surveys. Primary Sjögren’s syndrome was diagnosed at a median of 8.2 years (IQR 2.4–14.1) after inclusion. *Two-sided Fisher exact test. aPatients who were negative for anti-Sjögren’s syndrome related antigen A, Ro (anti-SSA), anti-Sjögren’s syndrome related antigen B, La (anti-SSB), antinuclear antibody (ANA) and rheumatoid factor (RF)