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Table 3 Association of patient and disease characteristics with short form-36 component summary scores in simple linear regression

From: Association of the lupus low disease activity state (LLDAS) with health-related quality of life in a multinational prospective study

Variable Physical component summary Mental component summary
Coeff* p 95% CI Coeff* p 95% CI
Country
 Australia reference - - 1.06 0.01 1.01–1.10
 China 1.14 <0.001 1.10–1.18 reference   
 Indonesia 1.11 <0.001 1.06–1.16 1.06 0.04 1.01–1.12
 Philippines 1.23 <0.001 1.18–1.28 1.20 <0.001 1.14–1.26
 Singapore 1.14 <0.001 1.10–1.18 1.13 <0.001 1.08–1.18
 Taiwan 1.14 <0.001 1.11–1.18 1.05 0.01 1.01–1.10
 Thailand 1.12 <0.001 1.09–1.16 1.04 0.10 0.99–1.08
Ethnicity
 Caucasian reference - - reference - -
 Asian 1.22 <0.001 1.18–1.26 1.03 0.19 0.99–1.08
Gender
 Female reference - - reference - -
 Male 1.02 0.42 0.98–1.06 0.99 0.95 0.95–1.05
Education
 Primary reference - - reference - -
 Secondary 1.05 0.001 1.02–1.08 1.01 0.47 0.98–1.05
 Tertiary 1.09 <0.001 1.06–1.13 1.06 0.002 1.02–1.09
Age at diagnosis (years) 0.997 <0.001 0.996–0.998 1.00 0.76 0.998–1.001
Disease duration (years) 0.997 <0.001 0.996–0.999 1.00 0.07 0.999–1.003
SLEDAI score 0.994 <0.001 0.992–0.996 0.997 0.03 0.994–0.999
Current organ activity
 CNS 0.82 0.003 0.73–0.93 0.93 0.32 0.79–1.08
 Renal 0.98 0.12 0.96–1.00 0.99 0.37 0.96–1.02
 MSK 0.89 <0.001 0.86–0.93 0.95 0.03 0.91–0.99
 Vasculitis 0.90 0.02 0.83–0.98 0.96 0.46 0.88–1.06
 Cutaneous 0.97 0.02 0.94–0.99 0.94 0.001 0.92–0.98
 Serositis 0.86 0.01 0.77–0.96 1.04 0.58 0.91–1.18
PGA (0–3) 0.94 <0.001 0.93–0.96 0.94 <0.001 0.93–0.96
Mild flare 0.95 0.002 0.92–0.98 0.98 0.25 0.94–1.02
Severe flare 0.89 <0.001 0.86–0.93 0.95 0.03 0.90–0.99
Prednisolone dose (mg) 0.998 <0.001 0.997–0.999 0.998 <0.001 0.997–0.999
LLDAS 1.04 <0.001 1.02–1.06 1.06 <0.001 1.04–1.09
SLICC-DI score 0.95 <0.001 0.94–0.96 0.99 0.43 0.99–1.01
  1. *Coefficient (Coeff) is based on the log-linear model and back-transformed using the exponential function. This represents (coeff-1)*100% increase/decrease in physical component summary or mental component summary scores for change in category (categorical variables), or (coeff-1)*100% change per one unit (continuous variables). Abbreviations: SLEDAI systemic lupus erythematosus disease activity index, MSK musculoskeletal, PGA physician global assessment, LLDAS lupus low disease activity state, SLICC Systemic Lupus International Collaborating Clinics, DI damage index, CNS central nervous system