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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Elevated serum autoantibodies against co-inhibitory PD-1 facilitate T cell proliferation and correlate with disease activity in new-onset systemic lupus erythematosus patients

Fig. 1

Elevated levels of PD-1 antibodies (IgG isotype) in new-onset SLE patients. The serum levels of PD-1 autoantibodies IgG isotype (a) and IgM isotype (b) from SLE patients (, n = 90), pSS patients (▲, n = 50), RA patients (■, n = 50), AS patients (, n = 25) and healthy controls (HC, , n = 80). All standards and samples were run in technical replicates, and readings were performed in duplicates. The optical density (OD) value for each individual is represented as a single point. Values represent the means ± SD. **p < 0.01, ***p < 0.001. AS ankylosing spondylitis, Ig immunoglobulin, HC healthy control, PD-1 programmed cell death protein, SS Sjogren’s syndrome, RA rheumatoid arthritis, SLE systemic lupus erythematosus 1

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