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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Chromatin landscapes and genetic risk for juvenile idiopathic arthritis

Fig. 3

Enrichment of transcription factors (TFs) in H3K4me1/H3K27ac mark regions. Heatmap of significantly enriched TFs with their transcription factor binding sites (TFBS) in H3K27ac or H3K4me1 peak regions in neutrophil cells (a) and CD4 + T cells (b), considering promoter and distal regions separately. TFs are ranked according to false discovery rate (FDR) (the lowest FDR with the highest rank) and normalized to (0,1) by dividing the absolute highest rank value for enrichment (red) and depletion (blue) separately. (normalized rank >0 = enrichment, <0 = depletion)

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