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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: Risk factors for flare and treatment of disease flares during pregnancy in rheumatoid arthritis and axial spondyloarthritis patients

Fig. 1

Disease activity over the course of pregnancy in patients with rheumatoid arthritis (RA) and axial spondyloarthritis (axSpA) treated with and without tumor necrosis factor inhibitors (TNFi) until early pregnancy. Disease activity is compared between patients who received TNFi until the positive pregnancy test and patients without TNFi treatment (TNFi-neg). The upper panels show Disease Activity Score in 28 joints based on C-reactive protein (DAS28-CRP) levels (a) and C-reactive protein (CRP) levels (b) in patients with RA (prepregnancy [pre]: number of patients [n] = 54, first trimester [1 T]: n = 59, second trimester [2 T]: n = 66, third trimester [3 T]: n = 64, postpartum [pp]: n = 53). The lower panels display Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP) levels (c) and CRP levels (d) in patients with axSpA (pre: n = 44, 1 T: n = 46, 2 T: n = 58, 3 T: n = 54, pp: n = 46). Box plots present the medians and the interquartile ranges. *P < 0.051

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