Skip to main content

Table 2 Dermal thickness in healthy subjects and patients classified as affected by limited cutaneous systemic sclerosis (lcSSc) on the basis of a normal Rodnan skin score at the upper arms, chest, abdomen and thighs

From: Subclinical dermal involvement is detectable by high frequency ultrasound even in patients with limited cutaneous systemic sclerosis

Dermal thickness

Healthy subjects

Patients with lcSSc

Patients with lcSSc with DT >2SD

Patients with lcSSc with DT >3SD

 

Mean ± SD (mm)

Mean + 2SD (mm)

Mean + 3SD (mm)

95% CI

lower, upper

99.73% CI

lower, upper

Mean ± SD (mm)

Number (%) (out of 50)

Number (%) (out of 50)

Right finger

0.70 ± 0.05

0.80

0.85

0.69, 0.72

0.68, 0.72

0.88 ± 0.14

32 (64)

25 (50)

Left finger

0.70 ± 0.06

0.82

0.88

0.69, 0.72

0.68, 0.72

0.88 ± 0.14

32 (64)

28 (56)

Right hand

0.71 ± 0.06

0.83

0.89

0.69, 0.72

0.68, 0.73

0.84 ± 0.12

23 (46)

13 (26)

Left hand

0.71 ± 0.06

0.83

0.89

0.69, 0.73

0.69, 0.74

0.86 ± 0.16

24 (48)

18 (36)

Right forearm

0.77 ± 0.05

0.87

0.92

0.75, 0.78

0.75, 0.79

0.98 ± 0.19

32 (64)

28 (56)

Left forearm

0.77 ± 0.05

0.87

0.92

0.75, 0.78

0.75, 0.79

0.99 ± 0.19

34 (68)

30 (60)

Right upper arm

0.82 ± 0.07

0.96

1.03

0.80, 0.83

0.79, 0.84

1.06 ± 0.16

37 (74)

23 (46)

Left upper arm

0.82 ± 0.06

0.94

1.00

0.80, 0.83

0.79, 0.84

1.07 ± 0.16

39 (78)

25 (50)

Chest

1.11 ± 0.03

1.17

1.20

1.11, 1.12

1.10, 1.13

1.23 ± 0.17

35 (70)

24 (48)

Abdomen

1.11 ± 0.02

1.15

1.17

1.11, 1.12

1.11, 1.12

1.28 ± 0.18

37 (74)

37 (74)

Right thigh

1.13 ± 0.21

1.55

1.76

1.08, 1.18

1.05, 1.21

1.18 ± 0.23

0

0

Left thigh

1.14 ± 0.20

1.54

1.74

1.08, 1.19

1.05, 1.22

1.18 ± 0.23

1 (2)

0

Right lower leg

0.92 ± 0.04

1.00

1.04

0.91, 0.93

0.90, 0.93

1.03 ± 0.13

25 (50)

16 (32)

Left lower leg

0.92 ± 0.05

1.02

1.07

0.90, 0.93

0.90, 0.93

1.03 ± 0.10

21 (42)

16 (32)

Right foot

0.87 ± 0.04

0.95

0.99

0.86, 0.88

0.86, 0.89

0.96 ± 0.13

24 (48)

17 (34)

Left foot

0.88 ± 0.04

0.96

1.00

0.87, 0.89

0.86, 0.89

0.97 ± 0.11

25 (50)

15 (30)

Zygoma

0.66 ± 0.05

0.76

0.81

0.65, 0.67

0.64, 0.68

0.85 ± 0.10

38 (76)

32 (64)

  1. Mean values, standard deviations (SD) and both 95% and 99.73% confidence intervals (CI) are reported. Of interest, patients with lcSSc had dermal thickness (DT) values greater than the normal range in healthy subjects (see mean +2SD and +3SD, and upper 95% and 99.73% CI reporting, respectively, the 5% and 0.27% chance that healthy subjects might have a dermal thickness above the range), also in those areas where the mRSS was zero