Table 3 Baseline phosphorylatad Janus kinase fluorescence intensities in peripheral blood leukocytes of patients and healthy reference subjects
Fluorescence | Cell type | Patients (n = 35) | Healthy control subjects (n = 17) | p Value |
|---|---|---|---|---|
pJAK1-PE | CD4+ T | 385 (92) | 335 (75) | 0.054 |
CD8+ T | 387 (89) | 365 (79) | 0.41 | |
CD19+ B | 549 (151) | 497 (121) | 0.23 | |
CD14+ Mo | 863 (240) | 737 (193) | 0.06 | |
pJAK2-PE | CD4+ T | 4443 (1446) | 3885 (1484) | 0.20 |
CD8+ T | 4282 (1792) | 4016 (1761) | 0.62 | |
CD19+ B | 7675 (3026) | 6340 (2680) | 0.12 | |
CD14+ Mo | 6571 (2703) | 4727 (1674) | 0.011 | |
pJAK3-PerCP | CD4+ T | 823 (197) | 773 (163) | 0.37 |
CD8+ T | 1350 (283) | 1388 (396) | 0.69 | |
CD19+ B | 1040 (214) | 994 (213) | 0.47 | |
CD14+ Mo | 2035 (442) | 1976 (385) | 0.65 | |
pTyk2-PE | CD4+ T | 380 (144) | 297 (41) | 0.001 |
CD8+ T | 342 (128) | 287 (43) | 0.037 | |
CD19+ B | 361 (177) | 295 (51) | 0.049 | |
CD14+ Mo | 1118 (342) | 827 (228) | <0.001 |