Skip to main content

Table 1 Baseline demographic, clinical, and laboratory characteristics of patients with undifferentiated arthritis (UA)

From: Increased galectin-3 may serve as a serologic signature of pre-rheumatoid arthritis while markers of synovitis and cartilage do not differ between early undifferentiated arthritis subsets

Characteristic

Total UA

(n = 111)

Pre-RA

(n = 23)

Non-RA

(n = 88)

p value

(pre-RA vs non- RA)

Sex (M/F)

25/86

5/18

20/68

0.92

Age (years)

48 (41–57)

50 (44–59)

47 (39–56)

0.28

Anti-CCP (positive/negative)

15/96

8/15

7/81

<0.001

Symptom duration (months)

6 (4–12)

5 (4–12)

7 (4.5–12)

0.50

C-reactive protein (mg/l)

4 (3–8)

8 (4–14)

4 (3–6)

<0.01

Swollen Joint Count (40)

0 (0–2)

1 (0–2)

0 (0–2)

0.03

Tender Joint Count (40)

9 (5–20)

15 (5–27)

8 (4.5–17)

0.05

Visual Analogue Scale – Doctor (0–100 mm)

12 (5–24)

24 (18–30)

9 (3–19)

<0.001

Visual Analogue Scale – Pain (0–100 mm)

36 (17–54)

54 (21–69)

34 (17–51)

0.01

Visual Analogue Scale – Global (0–100 mm)

41 (20–59)

60 (40–71)

36 (15–55)

<0.01

DAS28-CRP

3.6 (2.9–4.3)

4.1 (3.6–5.1)

3.5 (2.7–4.2)

<0.01

HAQ score (0–3)

0.4 (0–1)

0.75 (0–1.3)

0.37 (0–0.75)

0.05

MRI wrist synovitis score

3 (2–5)

5 (3.5–5.5)

3 (2–5)

<0.01

MRI wrist erosion score

3 (1–5)

4 (2–5.5)

2 (0–4)

0.01

MRI wrist bone marrow edema score

0 (0–1)

1 (0–2)

0 (0–0)

<0.01

  1. Results are presented as medians (interquartile range) unless otherwise stated
  2. Significant p values are indicated in bold typeface
  3. Anti-CCP antibodies to cyclic citrullinated peptides, DAS28-CRP Disease Activity Score in 28 joints including C-reactive peptide, HAQ Health Assessment Questionnaire, MRI magnetic resonance imaging, RA rheumatoid arthritis