Table 3 Univariate and multivariate analyses of galectin-3, PIIANP, and hyaluronan against biochemical, clinical, and imaging findings
Square root of galectin-3 (n = 111) | Log PIIANP (n = 111) | Log hyaluronan (n = 111) | |||||||
|---|---|---|---|---|---|---|---|---|---|
Variable | Beta coefficient | 95% CI | p value | Beta coefficient | 95% CI | p value | Beta coefficient | 95% CI | p value |
Univariate regression | |||||||||
Anti-CCP | – | – | –0.34 | –0.87 to 0.18 | 0.20 | ||||
C-reactive protein | 0.01 | 0.005 to 0.02 | 0.002 | – | 0.02 | (0.002 to 0.04) | 0.05 | ||
Swollen Joint count | – | –0.08 | –0.14 to –0.02 | 0.006 | – | ||||
Tender Joint count | – | 0.009 | –0.003 to 0.02 | 0.15 | –0.02 | (–0.04 to –0.001) | 0.04 | ||
VAS – Doctor | – | – | – | ||||||
VAS – Pain | 0.003 | –0.0006 to 0.007 | 0.10 | – | – | ||||
VAS – Global | – | –0.002 | –0.005 to 0.0008 | 0.15 | – | ||||
DAS28-CRP | – | – | –0.19 | –0.36 to –0.02 | 0.03 | ||||
HAQ score | – | – | – | ||||||
MRI synovitis score | – | – | 0.11 | 0.02 to 0.20 | 0.02 | ||||
MRI erosion score | – | 0.04 | 0.003 to 0.07 | 0.03 | 0.05 | (–0.01 to 0.11) | 0.11 | ||
MRI bone marrow edema score | 0.02 | –0.004 to 0.04 | 0.11 | – | – | ||||
Multivariate regression | |||||||||
Anti-CCP | – | – | –0.59 | –1.08 to –0.09 | 0.02 | ||||
VAS – Global | – | –0.003 | –0.007 to –0.00002 | 0.05 | – | ||||