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Table 5 The ordinal logistic regression analysis of clinical features # independently associated with the grade of sacroiliac joint damage

From: Monosodium urate crystal deposition associated with the progress of radiographic grade at the sacroiliac joint in axial SpA: a dual-energy CT study

Characteristics

Based on the left sacroiliac joint damage

Based on the right sacroiliac joint damage

Complex model 1

Simplified model 2

Complex model 3

Simplified model 4

AOR

95% CI

p value

AOR

95% CI

p value

AOR

95% CI

p value

AOR

95% CI

p value

AxSpA duration, per year

1.187

1.089–1.294

0.000

1.180

1.086–1.283

0.000

1.188

1.090–1.295

0.000

1.190

1.096–1.293

0.000

ESR, per mm/h

1.003

0.981–1.025

0.794

1.003

0.982–1.025

0.755

1.001

0.981–1.022

0.905

1.003

0.982–1.024

0.781

CRP, per mg/l

1.038

0.999–1.079

0.058

1.018

0.991–1.046

0.194

1.025

0.987–1.065

0.196

1.008

0.981–1.036

0.576

Total back pain, per score

1.428

1.040–1.962

0.028

1.246

0.975–1.591

0.078

1.315

0.959–1.803

0.089

1.166

0.916–1.484

0.212

PGA of disease activity, per score

1.040

0.784–1.380

0.786

0.975

0.746–1.275

0.856

1.023

0.780–1.342

0.868

0.970

0.751–1.252

0.815

Pain and swelling of peripheral arthritis, per score

1.517

0.795–2.897

0.207

1.356

0.725–2.534

0.341

1.858

0.978–3.532

0.059

1.657

0.890–3.084

0.111

Duration of morning stiffness, per score

0.723

0.519–1.008

0.056

0.682

0.494–0.942

0.020

0.836

0.607–1.150

0.271

0.792

0.581–1.079

0.139

ASDAS, per score

0.492

0.179–1.354

0.170

NA

NA

NA

0.526

0.194–1.429

0.208

NA

NA

NA

BASFI, per score

3.837

2.263–6.506

0.000

3.800

2.250–6.417

0.000

3.092

1.896–5.044

0.000

3.034

1.870–4.922

0.000

Ever use of biologic DMARDs, vs never

  ≥ 12 months

1.051

0.308–3.581

0.937

1.144

0.337–3.885

0.829

1.425

0.417–4.872

0.572

1.414

0.421–4.754

0.575

  ≤ 12 months

0.961

0.333–2.778

0.942

1.098

0.385–3.132

0.861

0.971

0.329–2.866

0.958

1.020

0.357–2.916

0.971

  ≤ 6 months

1.999

0.806–4.962

0.135

1.830

0.745–4.495

0.188

2.461

0.976–6.204

0.056

2.128

0.869–5.211

0.099

 Never

NA

NA

NA

NA

NA

NA

NA

NA

NA

NA

NA

NA

MSU crystallization positive, vs negative

 Left sacroiliac joint

0.895

0.391–2.049

0.794

NA

NA

NA

NA

NA

NA

NA

NA

NA

 Right sacroiliac joint

NA

NA

NA

NA

NA

NA

1.291

0.542–3.075

0.565

NA

NA

NA

Volume of MSU crystallization, per cm3

 Left sacroiliac joint

2.018

1.144–3.560

0.015

1.920

1.209–3.049

0.006

NA

NA

NA

NA

NA

NA

 Right sacroiliac joint

NA

NA

NA

NA

NA

NA

1.387

1.022–1.882

0.036

1.418

1.075–1.870

0.014

  1. Complex model 1 and 3, variables with p < 0.05 in bivariate analysis were included based on the radiographic grade at each sacroiliac joint; simplified model 2 and 4, the models with the repeated variables of the ASDAS score and MSU crystals deposits positive were excluded
  2. AxSpA axial spondyloarthritis, ESR erythrocyte sedimentation rate, CRP C-reactive protein, PGA patient’s global assessment, ASDAS Ankylosing Spondylitis Disease Activity Score, BASFI Bath Ankylosing Spondylitis Functional Index, DMARDs disease-modifying anti-rheumatic drugs, MSU monosodium urate, AOR adjusted odds ratios, 95% CI 95% confidence interval, NA not available
  3. #Including clinical variables and the DECT scans results