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Table 5 The ordinal logistic regression analysis of clinical features # independently associated with the grade of sacroiliac joint damage

From: Monosodium urate crystal deposition associated with the progress of radiographic grade at the sacroiliac joint in axial SpA: a dual-energy CT study

Characteristics Based on the left sacroiliac joint damage Based on the right sacroiliac joint damage
Complex model 1 Simplified model 2 Complex model 3 Simplified model 4
AOR 95% CI p value AOR 95% CI p value AOR 95% CI p value AOR 95% CI p value
AxSpA duration, per year 1.187 1.089–1.294 0.000 1.180 1.086–1.283 0.000 1.188 1.090–1.295 0.000 1.190 1.096–1.293 0.000
ESR, per mm/h 1.003 0.981–1.025 0.794 1.003 0.982–1.025 0.755 1.001 0.981–1.022 0.905 1.003 0.982–1.024 0.781
CRP, per mg/l 1.038 0.999–1.079 0.058 1.018 0.991–1.046 0.194 1.025 0.987–1.065 0.196 1.008 0.981–1.036 0.576
Total back pain, per score 1.428 1.040–1.962 0.028 1.246 0.975–1.591 0.078 1.315 0.959–1.803 0.089 1.166 0.916–1.484 0.212
PGA of disease activity, per score 1.040 0.784–1.380 0.786 0.975 0.746–1.275 0.856 1.023 0.780–1.342 0.868 0.970 0.751–1.252 0.815
Pain and swelling of peripheral arthritis, per score 1.517 0.795–2.897 0.207 1.356 0.725–2.534 0.341 1.858 0.978–3.532 0.059 1.657 0.890–3.084 0.111
Duration of morning stiffness, per score 0.723 0.519–1.008 0.056 0.682 0.494–0.942 0.020 0.836 0.607–1.150 0.271 0.792 0.581–1.079 0.139
ASDAS, per score 0.492 0.179–1.354 0.170 NA NA NA 0.526 0.194–1.429 0.208 NA NA NA
BASFI, per score 3.837 2.263–6.506 0.000 3.800 2.250–6.417 0.000 3.092 1.896–5.044 0.000 3.034 1.870–4.922 0.000
Ever use of biologic DMARDs, vs never
  ≥ 12 months 1.051 0.308–3.581 0.937 1.144 0.337–3.885 0.829 1.425 0.417–4.872 0.572 1.414 0.421–4.754 0.575
  ≤ 12 months 0.961 0.333–2.778 0.942 1.098 0.385–3.132 0.861 0.971 0.329–2.866 0.958 1.020 0.357–2.916 0.971
  ≤ 6 months 1.999 0.806–4.962 0.135 1.830 0.745–4.495 0.188 2.461 0.976–6.204 0.056 2.128 0.869–5.211 0.099
 Never NA NA NA NA NA NA NA NA NA NA NA NA
MSU crystallization positive, vs negative
 Left sacroiliac joint 0.895 0.391–2.049 0.794 NA NA NA NA NA NA NA NA NA
 Right sacroiliac joint NA NA NA NA NA NA 1.291 0.542–3.075 0.565 NA NA NA
Volume of MSU crystallization, per cm3
 Left sacroiliac joint 2.018 1.144–3.560 0.015 1.920 1.209–3.049 0.006 NA NA NA NA NA NA
 Right sacroiliac joint NA NA NA NA NA NA 1.387 1.022–1.882 0.036 1.418 1.075–1.870 0.014
  1. Complex model 1 and 3, variables with p < 0.05 in bivariate analysis were included based on the radiographic grade at each sacroiliac joint; simplified model 2 and 4, the models with the repeated variables of the ASDAS score and MSU crystals deposits positive were excluded
  2. AxSpA axial spondyloarthritis, ESR erythrocyte sedimentation rate, CRP C-reactive protein, PGA patient’s global assessment, ASDAS Ankylosing Spondylitis Disease Activity Score, BASFI Bath Ankylosing Spondylitis Functional Index, DMARDs disease-modifying anti-rheumatic drugs, MSU monosodium urate, AOR adjusted odds ratios, 95% CI 95% confidence interval, NA not available
  3. #Including clinical variables and the DECT scans results
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