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Table 2 Univariate and multivariate associations with the primary analysis outcome

From: Development of a clinical prediction algorithm for knee osteoarthritis structural progression in a cohort study: value of adding measurement of subchondral bone density

Characteristic

Univariate odds ratio (95% CI)

Multivariable odds ratio (95% CI)

Female

1.18 (0.66, 2.11)

1.06 (0.56, 2.01)

Age, yearsa

1.58 (1.18, 2.16)

1.45 (1.02, 2.08)

Body mass index kg/m2 a

1.20 (0.90, 1.59)

1.32 (0.95, 1.84)

Knee paina

1.28 (0.96, 1.70)

1.06 (0.77, 1.47)

Recent injury

2.14 (0.32, 8.60)

2.58 (0.39, 16.92)

Hand OA

3.12 (1.74, 5.72)

2.68 (1.39, 5.19)

M:L BMDa

1.94 (1.47, 2.58)

1.76 (1.32, 2.35)

Radiographic knee OA

3.33 (1.50, 8.87)

2.20 (0.88, 5.50)

  1. OA osteoarthritis, M:L BMD ratio medial-to-lateral tibial plateau bone mineral density ratio
  2. aOdds ratio estimates per 1 standard deviation change in predictor