Skip to main content

Table 3 Improvement measures comparing base and BMD models in primary analysis

From: Development of a clinical prediction algorithm for knee osteoarthritis structural progression in a cohort study: value of adding measurement of subchondral bone density

Improvement measure Outcome Base model BMD model Comparison
Net reclassification improvement    Net % improvement NRI (95% CI)
OA progression Ref 22% 0.49 (0.20, 0.77)
No OA progression Ref 27%  
Integrated discrimination improvement   Base model average prediction BMD model average prediction IDI (95% CI)
OA progression 0.12 0.16 0.04 (0.01, 0.06)
No OA progression 0.09 0.09  
  1. BMD bone mineral density, OA osteoarthritis