Table 4 Prediction of responder status at short term (2 weeks) and longer term (6 months) follow up, by baseline imaging characteristics

 Synovitis maximal score (0–3)

109

0.82 (0.32 to 2.13)

0.689

109

0.43 (0.17 to 1.12)

0.084

 Bone marrow lesion maximal score (0–3)

109

0.76 (0.49 to 1.19)

0.231

109

1.12 (0.66 to 1.92)

0.668

 Bone attrition maximal score (0–3)

109

0.94 (0.56 to 1.57)

0.804

109

0.59 (0.32 to 1.10)

0.097

 Cartilage damage maximal score (0–6)

109

0.98 (0.75 to 1.27)

0.869

109

1.03 (0.74 to 1.42)

0.873

 Cyst maximal score (0–3)

108

0.74 (0.46 to 1.20)

0.222

108

1.27 (0.72 to 2.22)

0.408

 Menisci damage maximal score (0–6)

109

0.95 (0.74 to 1.20)

0.647

109

0.74 (0.55 to 0.98)*

0.039

 Osteophyte maximal score (0–7)

109

1.13 (0.86 to 1.49)

0.386

109

0.98 (0.70 to 1.38)

0.919

 Synovial effusion (0–3)

109

0.83 (0.52 to 1.31)

0.420

109

0.79 (0.44 to 1.41)

0.421

 Synovial tissue volume (per 1000 mm³)

111

1.00 (1.00 to 1.00)

0.612

111

0.96 (0.88 to 1.04)

0.327

 Tibiofemoral KL score (0–4)

187

0.79 (0.49 to 1.28)

0.341

187

0.52 (0.30 to 0.91)*

0.021

 Patellofemoral KL score (0–4)

188

0.86 (0.60 to 1.22)

0.391

188

0.80 (0.54 to 1.19)

0.269

 Overall KL maximal score^a (0–4)

188

0.72 (0.43 to 1.20)

0.205

188

0.43 (0.23 to 0.82)*

0.010

 Lateral tibiofemoral JSN score (0–3)

186

1.27 (0.79 to 2.03)

0.327

186

0.86 (0.51 to 1.45)

0.569

 Medial tibiofemoral JSN score (0–3)

187

0.91 (0.59 to 1.40)

0.661

187

0.69 (0.42 to 1.15)

0.154

 Patellofemoral JSN score (0–3)

179

0.83 (0.59 to 1.16)

0.265

179

0.85 (0.56 to 1.28)

0.425

 Overall JSN maximal score^b (0–3)

187

0.75 (0.49 to 1.16)

0.196

187

0.60 (0.36 to 0.99)*

0.047

 Knee mal-alignment angle (per degree)

192

0.98 (0.92 to 1.04)

0.481

192

1.01 (0.94 to 1.08)

0.801