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Table 3 Baseline all-cause healthcare resource utilization and cost characteristics (postmatching)

From: Costs associated with failure to respond to treatment among patients with rheumatoid arthritis initiating TNFi therapy: a retrospective claims analysis

 

Responders (n = 2337)

Nonresponders (n = 2337)

p Valuea

Standardized differenceb

Inpatient hospitalization, n (%) with at least one visit

197 (8.4%)

249 (10.7%)

0.010

0.08

ED encounters, n (%) with at least one visit

374 (16.0%)

418 (17.9%)

0.086

0.05

Outpatient visits, n (%) with at least one visit

2332 (99.8%)

2332 (99.8%)

1.000

0.00

 Rheumatologist office visit, n (%)

1692 (72.4%)

1623 (69.4%)

0.026

0.07

 Physical/occupational therapy visits, n (%)

506 (21.7%)

530 (22.7%)

0.398

0.03

Pharmacy fills, n (%) with at least one fill

2298 (98.3%)

2309 (98.8%)

0.176

0.04

 Oral glucocorticoids

1579 (67.6%)

1699 (72.7%)

<0.001

0.11

 Antihypertensives

887 (38.0%)

974 (41.7%)

0.009

0.08

 Antidiabetics

206 (8.8%)

184 (7.9%)

0.245

0.03

 Antihyperlipidemics

512 (21.9%)

497 (21.3%)

0.594

0.02

 Antidepressives

537 (23.0%)

643 (27.5%)

<0.001

0.11

 Pain medicationsc

1853 (79.3%)

1891 (80.9%)

0.164

0.04

Number of pharmacy fills per patient, mean (SD)

40.7 (28.11)

43.9 (30.59)

<0.001

0.11

csDMARDs, n (%) with at least one fill

2135 (91.4%)

2135 (91.4%)

1.000

0.00

 Hydroxychloroquine

701 (30.0%)

658 (28.2%)

0.166

0.04

 Leflunomide

301 (12.9%)

322 (13.8%)

0.366

0.03

 Methotrexate

1849 (79.1%)

1854 (79.3%)

0.857

0.01

 Minocycline

27 (1.2%)

25 (1.1%)

0.780

0.01

 Sulfasalazine

266 (11.4%)

270 (11.6%)

0.854

0.01

Total medical costs, $ per person, mean (SD)

6819 (14,807)

7730 (15,929)

0.043

0.06

 Inpatient costs, $ per person, mean (SD)

1927 (10,790)

2068 (10,636)

0.653

0.01

 ED costs, $ per person, mean (SD)

242 (938)

336 (1527)

0.012

0.07

 Outpatient costs, $ per person, mean (SD)

4638 (7152)

5313 (9501)

0.006

0.08

Total pharmacy costs, $ per person, mean (SD)

1639 (2433)

1799 (3020)

0.046

0.06

  1. csDMARD Conventional synthetic disease-modifying antirheumatic drug, ED Emergency department
  2. a χ2 tests were used to determine a statistical differences across categorical variables; t tests were used for continuous variables
  3. b Standardized difference = difference in means or proportions divided by standard error, in absolute value
  4. c Pain medications include opioids, nonsteroidal anti-inflammatory drugs, and others, and exclude disease-modifying antirheumatic drugs
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Arthritis Research & Therapy

ISSN: 1478-6362

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