Table 4 List of a priori Clinically Defined Predictors and their Measurement

 Number ESR tests

85651, 85652

CPT

CDW.OutpatProcedure

 Number CRP tests

86140

CPT

CDW.OutpatProcedure

 aCCP – (Y/N)

86200

CPT

CDW.OutpatProcedure

 RF – (Y/N)

86431

CPT

CDW.OutpatProcedure

 Number. complete blood counts

85025

CPT

CDW.OutpatProcedure

 Number. chemistry panels ordered or any electrolyte

80053, 82248, 82465, 82977, 83540, 83615, 84100, 84478, 84550

CPT

CDW.OutpatProcedure

 Radiographs (Y/N)

70010-79999

CPT

CDW.OutpatProcedure

 Number radiographs

Count of 70010-79999

CPT

CDW.OutpatProcedure

 Hand or foot (Y/N) (toes, fingers, wrist)

73620, 73630, 73650, 73660, 73100, 73110,73120, 73130

CPT

CDW.OutpatProcedure

 C-spine (Y/N)

72040, 75052

CPT

CDW.OutpatProcedure

 Other bone x-ray (Y/N)

Master file

CPT

CDW.OutpatProcedure

 Any visit

Any

stopcode

CDW.outpatVisit

 Rheumatology

314

stopcode

CDW.outpatVisit

 Primary care

323, 342

stopcode

CDW.outpatVisit

 Orthopedic

60, 509

stopcode

CDW.outpatVisit

 Physical Rehabilitation

201, 250

stopcode

CDW.outpatVisit

 Occupational Therapy

21, 206, 460

stopcode

CDW.outpatVisit

 Number ED visits

130, 101

stopcode

CDW.outpatVisit

 Number Inpatient stay

Row count per person

Admission date

Inpatient.inpatient

 Unique Drug class codes

Row count per person

VAdrugclasscode

CDW.Rxoutpat

 Any surgery

10021-6990

CPT

 Any surgery

Master file

ICD9

CDW.outpatProcedure, inpatProcedure, inpatientCPT

 Hand surgery

26500, 26502, 26504, 26494, 26989

CPT

CDW.Outpat.Procedure, inpatientCPT

 Hand surgery

Master file^a

ICD9

CDW.inpatientProcedure

 Any orthopedic (include spine) surgery

Master file

CPT

CDW.inpatientCPT, Outpat.Procedure

 Joint injections

Master file

Jcode

CDW.Outpat.Procedure, inpatientCPT

 RDCI RA comorbidity score

See published paper

ICD9

CDW.outpatDiagnosis

 Rheumatoid lung involvement

714.81

ICD9

CDW.outpatDiagnosis

 Felty’s syndrome

714.1

ICD9

CDW.outpatDiagnosis

 Sjogrens

710.2

ICD9

CDW.outpatDiagnosis

 Cane (Y/N)

Master file

CPT/ICD9 procedure

CDW.outpatProcedure, inpatProcedure

 Crutch (Y/N)

Master file

CPT/ICD9 procedure

CDW.outpatProcedure, inpatProcedure

 Walker (Y/N)

Master file

CPT/ICD9 procedure

CDW.outpatProcedure, inpatProcedure

 Wheelchair (Y/N)

Master file

CPT/ICD9 procedure

CDW.outpatProcedure, inpatProcedure

 Other Assist Device (Y/N)

Master file

CPT/ICD9 procedure

CDW.outpatProcedure, inpatProcedure

 Number NSAID

MS102

VA drug Class

CDW.Rxoutpatfill

 Number Non-biologic DMARD

String search - list below

drugnamewithoutdose

CDW.Rxoutpatfill

 Methotrexate (Y/N)

String search

drugnamewithoutdose

CDW.Rxoutpatfill

 Leflunomide (Y/N)

String search

drugnamewithoutdose

CDW.Rxoutpatfill

 Sulfasalazine (Y/N)

String search

drugnamewithoutdose

CDW.Rxoutpatfill

 Hydroxychloroquine (Y/N)

String search

drugnamewithoutdose

CDW.Rxoutpatfill

 Azathioprine (Y/N)

String search

drugnamewithoutdose

CDW.Rxoutpatfill

 TNFi (Y/N)

String search: etanercept, adalimumab, infliximab, golimumab, certolizumab

drugnamewithoutdose

CDW.MCA, Rxoutpatfill, outpatProcedure, TIU notes

 Other biologics

rituximab, abatacept, anakinra, tocilizumab,

drugnamewithoutdose

CDW.MCA, Rxoutpatfill, outpatProcedure, TIU notes

 Tofacitinib (Y/N)

String search

drugnamewithoutdose

CDW.Rxoutpatfill

 Glucocorticosteroids (Y/N and Dose)

HS051

VA drug Class

CDW.MCA and Rxoutpatfill

 Minor DMARDs (Any Y/N)

Doxycyline, minocycline, auranofin, d-penicillamine, cyclosporine

drugnamewithoutdose

CDW.Rxoutpatfill

 Smoking cessation medication (Y/N)

Chantix Nicotine substitutes

Drugnamewithoutdose

CDW.Rxoutpatfill

 Days since start med

All meds

drugnamewithoutdose

CDW.Rxoutpatfill

 Days since end med (90-day gap to end)

All meds

drugnamewithoutdose

CDW.Rxoutpatfill

 PDC from start therapy to end of observation period

All meds

drugnamewithoutdose

CDW.Rxoutpatfill

 Age

Age

DOB

CDW.patient

 Gender

M/F

Gender

CDW.patient