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Table 3 Contributions of different variables to intergroup differences of patients with rheumatoid arthritis versus healthy subjects based on analysis of variance

From: Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers

Variable

RAa versus control

Activityb

F

Pr (>F)

F

Pr (>F)

ACPA

48.4

<0.001

1.46

0.23

n-cirDNA

3.73

0.06

1.67

0.20

n-csbDNA

6.07

0.02

0.28

0.60

m-cirDNA

3.95

0.05

0.35

0.55

m-csbDNA

17.7

0.00005

2.59

0.11

C-reactive protein

30.3

2.64e-07

1.27

0.26

Rheumatoid factor

16.3

0.0001

1.81

0.18

  1. Abbreviations: ACPA Anticitrullinated protein/peptide antibodies, m-cirDNA Cell-free mitochondrial circulating DNA, m-csbDNA Mitochondrial cell surface-bound DNA, n-cirDNA Cell-free nuclear circulating DNA, n-csbDNA Nuclear cell surface-bound DNA, RA Rheumatoid arthritis
  2. a RA group 1 (n = 74) (see Table 1)
  3. b Patients with RA were divided into two groups according to RA activity score: group 1 with low and moderate activity (classes I–II DAS28) and group 2 with high activity of the disease (class III DAS28)
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Arthritis Research & Therapy

ISSN: 1478-6362

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