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Table 3 Contributions of different variables to intergroup differences of patients with rheumatoid arthritis versus healthy subjects based on analysis of variance

From: Circulating DNA in rheumatoid arthritis: pathological changes and association with clinically used serological markers

Variable RAa versus control Activityb
F Pr (>F) F Pr (>F)
ACPA 48.4 <0.001 1.46 0.23
n-cirDNA 3.73 0.06 1.67 0.20
n-csbDNA 6.07 0.02 0.28 0.60
m-cirDNA 3.95 0.05 0.35 0.55
m-csbDNA 17.7 0.00005 2.59 0.11
C-reactive protein 30.3 2.64e-07 1.27 0.26
Rheumatoid factor 16.3 0.0001 1.81 0.18
  1. Abbreviations: ACPA Anticitrullinated protein/peptide antibodies, m-cirDNA Cell-free mitochondrial circulating DNA, m-csbDNA Mitochondrial cell surface-bound DNA, n-cirDNA Cell-free nuclear circulating DNA, n-csbDNA Nuclear cell surface-bound DNA, RA Rheumatoid arthritis
  2. a RA group 1 (n = 74) (see Table 1)
  3. b Patients with RA were divided into two groups according to RA activity score: group 1 with low and moderate activity (classes I–II DAS28) and group 2 with high activity of the disease (class III DAS28)