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Table 2 Patient characteristics at time of enthesitis-related arthritis classification

From: Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches

 

All subjects (n = 234)

Demographics, median (IQR) or n (%)

 Age in years

11.6 (9.8–13.7)

 Sex, male

169 (72.2)

 Race, Caucasian

194 (82.9)

 Family history of HLA-B27-associated disease

36 (15.4)

Clinical characteristics, median (IQR) or n (%)

 HLA-B27 positivity

135 (59.2)

 Active joint count

2 (1–4)

 Tender entheses count

2 (1–4)

 MRI-defined sacroiliitis (n = 45 with imaging)

25 (55.6)

 Polyarticular onset

52 (22.2)

 ANA-positive

49 (23.4)

 CRP, abnormal/elevated

39 (26.9)

 ESR, abnormal/elevated

93 (45.8)

Patient-/physician-reported outcomes, median (IQR)

 Physician global disease activity assessment (0–10)

2.5 (2–4)

 Juvenile Spondyloarthritis Disease Activity Index (JSpADA) (0–8)

3 (2.5–4)

 Juvenile Arthritis Disease Activity Score (cJADAS), excluding ESR (0–30)

9 (5–14)

 Patient/parent global disease activity assessment (0–10)

4 (2–6)

 Function (CHAQ) (0–3)

0.563 (0–1)

 Patient/parent pain assessment (0–10)

4 (2–7)

  1. Abbreviations: IQR Interquartile range, HLA Human leukocyte antigen, MRI Magnetic resonance imaging, ANA Antinuclear antibody, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, CHAQ Childhood Health Assessment Questionnaire
  2. Denominators for clinical characteristics varied because of missing data: HLA-B27 status (n = 228), magnetic resonance imaging-defined sacroiliitis (n = 45), ANA (n = 209), CRP (n = 145), ESR (n = 203), physician global disease activity assessment (n = 126), JSpADA (n = 116), patient/parent global disease activity assessment (n = 102), CHAQ (n = 120), patient/parent pain assessment (n = 129), cJADAS (JADAS3–10) (n = 86)
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