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Table 2 Patient characteristics at time of enthesitis-related arthritis classification

From: Multicenter inception cohort of enthesitis-related arthritis: variation in disease characteristics and treatment approaches

  All subjects (n = 234)
Demographics, median (IQR) or n (%)
 Age in years 11.6 (9.8–13.7)
 Sex, male 169 (72.2)
 Race, Caucasian 194 (82.9)
 Family history of HLA-B27-associated disease 36 (15.4)
Clinical characteristics, median (IQR) or n (%)
 HLA-B27 positivity 135 (59.2)
 Active joint count 2 (1–4)
 Tender entheses count 2 (1–4)
 MRI-defined sacroiliitis (n = 45 with imaging) 25 (55.6)
 Polyarticular onset 52 (22.2)
 ANA-positive 49 (23.4)
 CRP, abnormal/elevated 39 (26.9)
 ESR, abnormal/elevated 93 (45.8)
Patient-/physician-reported outcomes, median (IQR)
 Physician global disease activity assessment (0–10) 2.5 (2–4)
 Juvenile Spondyloarthritis Disease Activity Index (JSpADA) (0–8) 3 (2.5–4)
 Juvenile Arthritis Disease Activity Score (cJADAS), excluding ESR (0–30) 9 (5–14)
 Patient/parent global disease activity assessment (0–10) 4 (2–6)
 Function (CHAQ) (0–3) 0.563 (0–1)
 Patient/parent pain assessment (0–10) 4 (2–7)
  1. Abbreviations: IQR Interquartile range, HLA Human leukocyte antigen, MRI Magnetic resonance imaging, ANA Antinuclear antibody, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, CHAQ Childhood Health Assessment Questionnaire
  2. Denominators for clinical characteristics varied because of missing data: HLA-B27 status (n = 228), magnetic resonance imaging-defined sacroiliitis (n = 45), ANA (n = 209), CRP (n = 145), ESR (n = 203), physician global disease activity assessment (n = 126), JSpADA (n = 116), patient/parent global disease activity assessment (n = 102), CHAQ (n = 120), patient/parent pain assessment (n = 129), cJADAS (JADAS3–10) (n = 86)