Table 1 Demographic data and clinical features of 411 Chinese TAK patients
Patient number | |
|---|---|
Gender | |
Female | 325 (79.1%) |
Male | 86 (20.9%) |
Age at onset (years) | 23.0 (18.0, 30.0)a |
Duration of disease at first admission (months) | 21.0 (6.0, 60.0)a |
Constitutional findings | |
Fever | 128 (31.1%) |
Malaise | 122 (29.7%) |
Weight loss | 82 (20.0%) |
Symptoms | |
Arthralgia | 37 (9.0%) |
Skin rash | 32 (7.8%) |
Vascular findings | |
Bruit of carotid arteries | 257 (62.5%) |
Hypertension | 209 (50.9%) |
Asymmetric pulsation | 158 (24.6%) |
Claudication | |
Upper limbs | 60 (14.6%) |
Lower limbs | 57 (13.9%) |
Gangrene | 2 (0.5%) |
Cardiac findings | |
Valvar lesions | 201 (48.9%) |
Left ventricle hypertrophy on ECG | 58 (14.4%) |
Heart failure | 61 (14.8%) |
Pericardial effusion | 30 (7.3%) |
Myocardial lesions | 26 (6.3%) |
Angina | 14 (3.4%) |
Myocardial infarction | 3 (0.7%) |
Renal abnormalities | |
Nephrotic-range proteinuria | 13 (3.2%) |
Renal dysfunction | 47 (11.4%) |
Neurological symptoms | |
Headache | 125 (30.4%) |
Ischemic stroke | 22 (5.4%) |
Syncope | 49 (11.9%) |
Ophthalmoscope findings | |
Hypertensive retinopathy | 31/165b (18.8%) |
TAK-related retinopathy | 23/165b (13.9%) |
Ischemic changes | 11/165b (6.7%) |
Vasculitis presentations | 11/165b (6.7%) |
Others | 3/165b (1.8%) |
Angiographic classification | |
Type I | 91 (22.1%) |
Type IIa | 16 (3.9%) |
Type IIb | 16 (3.9%) |
Type III | 12 (2.9%) |
Type IV | 26 (6.3%) |
Type V | 250 (60.8%) |
Laboratory findings | |
Level of ESR (mm/h) | 26.0 (11.0, 65.0)a |
Level of CRP (mg/L) | 12.8 (3.4, 44.8)a |
Level of hs-CRP (mg/L) | 8.8 (2.0, 12.5)a |
Level of WBC (109/L) | 8.2 (6.6, 11.0)a |
Level of Hgb (g/L) | 121 (108, 135)a |