Fig. 5

Successive changes of CD4⁺ T-cell subsets after vaccination. Four healthy donors were inoculated with influenza vaccine. The indicated T-cell subsets were evaluated on day 0 (before vaccination), day 7, and day 14. * P < 0.05; ** P < 0.01. P values were calculated by one-way analysis of variance and Tukey’s multiple-comparisons test. CD Cluster of differentiation, LAG3 Lymphocyte activation gene 3, ns Not significant, T _FH Follicular helper T cell, Th Helper T cell, Treg Regulatory T cell