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Table 1 Gene Ontology (GO) biological processes enriched in genes differentially expressed among women with RA who improved during pregnancy

From: Pregnancy-induced gene expression changes in vivo among women with rheumatoid arthritis: a pilot study

GO biological process

Gene count

q value

Immune system process

55

7.9 × 10−14

Response to stress

54

9.1 × 10−6

Defense response

35

1.5 × 10−8

Immune response

34

2.2 × 10−8

Multiorganism process

34

6.7 × 10−6

Response to other organism

27

1.4 × 10−9

Response to biotic stimulus

27

2.9 × 10−9

Innate immune response

22

5.6 × 10−7

Response to bacterium

16

9.0 × 10−6

Erythrocyte differentiation

10

6.5 × 10−7

  1. Of the 161 genes differentially expressed (with FC≥2) between T0 and T3 among pregDASimproved women, several were enriched in GO biological processes relating to immune functions. (Note: These 161 genes included some that were also differentially expressed among healthy women and pregDASworse women.)