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Table 2 Gene Ontology biological processes enriched in genes differentially expressed among women with RA who improved during pregnancy, but not among those who worsened

From: Pregnancy-induced gene expression changes in vivo among women with rheumatoid arthritis: a pilot study

GO biological process

Gene count

q value

Immune system process

43

4.7 × 10−10

Defense response

26

9.6 × 10−6

Immune response

24

5.0 × 10−5

Innate immune response

18

8.0 × 10−6

Response to other organism

17

6.7 × 10−5

Response to biotic stimulus

17

1.0 × 10−4

Hemopoiesis

15

2.0 × 10−4

Homeostasis of number of cells

11

6.9 × 10−6

Myeloid cell differentiation

11

7.1 × 10−5

Erythrocyte differentiation

10

2.5 × 10−7

  1. The 130 genes that were differentially expressed (with FC≥2) between T0 and T3 among pregDASimproved, but not among pregDASworse women, included several that were enriched in GO biological processes relating to immune functions