Characteristic | Value |
---|---|
Baseline | Â |
 Number of participants | 153 |
 Age, years | 46.7 (9.3) |
 Female, n (%) | 125 (81.7) |
 Body mass index, kg/m2 | 32.4 (8.9) |
   Range | 16.9 to 54.9 |
 Obesity, n (%) | 82 (53.6) |
 WOMAC, median |  |
   Pain (out of 500) | 15 |
   Stiffness (out of 200) | 5 |
   Function (out of 1700) | 52 |
 Strenuous physical activity, n (%) | 119 (77.8) |
 Bone mineral density |  |
  Total body | |
   Bone mineral density, g/cm2 | 1.24 (0.10) |
   T-score | 1.18 (1.22) |
   T-score, range | −1.90 to 4.40 |
   Osteopenia, n (%)/osteoporosis, n (%) | 4 (2.6)/0 (0) |
  Spine | |
   Bone mineral density, g/cm2 | 1.26 (0.17) |
   T-score | 0.46 (1.44) |
   T-score, range | −2.30 to 4.80 |
   Osteopenia, n (%)/osteoporosis, n (%) | 19 (12.4)/0 (0) |
  Total hip | |
   Bone mineral density, g/cm2 | 1.09 (0.16) |
   T-score | 0.63 (1.29) |
   T-score, range | −2.40 to 4.50 |
   Osteopenia, n (%)/osteoporosis, n (%) | 13 (8.5)/0 (0) |
  Tibial cartilage volume, mm3 | |
   Medial | 996 (252) |
   Lateral | 1299 (369) |
  Tibiofemoral cartilage defects, n (%) | |
   Medial | 96 (62.7) |
   Lateral | 135 (88.2) |
  Tibial bone area, mm2 | |
   Medial | 1888 (254) |
   Lateral | 1455 (211) |
Change | Â |
  Number of participants | 139 |
  Annual change in tibial cartilage volume, % | |
   Medial | 1.5 (1.7) |
   Lateral | 1.0 (1.5) |
  Progression of tibiofemoral cartilage defects, n (%) | |
   Medial | 23 (16.5) |
   Lateral | 26 (18.7) |