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Table 3 Association between baseline systemic bone mineral density and progression of tibiofemoral cartilage defects

From: Associations between systemic bone mineral density and early knee cartilage changes in middle-aged adults without clinical knee disease: a prospective cohort study

 

Univariable analysis

Odds ratio (95% CI)

P

Multivariable analysisa

Odds ratio (95% CI)

P

Total body BMD

 Medial

1.25 (0.80, 1.94)

0.33

1.71 (0.94, 3.08)

0.08

 Lateral

1.19 (0.78, 1.81)

0.42

1.45 (0.84, 2.50)

0.18

Spine BMD

 Medial

1.38 (1.07, 1.77)

0.01

1.45 (1.10, 1.91)

0.01

 Lateral

1.19 (0.94, 1.52)

0.15

1.30 (1.00, 1.67)

0.049

Total hip BMD

 Medial

1.33 (1.00, 1.75)

0.05

1.63 (1.10, 2.41)

0.02

 Lateral

1.22 (0.93, 1.59)

0.15

1.53 (1.08, 2.18)

0.02

  1. BMD (bone mineral density) was assessed in g/10 cm2 so that one unit change in BMD approximated one standard deviation change in BMD. aAdjusted for gender, baseline age, body mass index, strenuous physical activity, respective baseline tibial cartilage volume and bone area, and time between scans