Skip to main content

Table 3 Overview of the medication applied in the TAK cohort

From: TNF inhibitors appear to inhibit disease progression and improve outcome in Takayasu arteritis; an observational, population-based time trend study

Treatment

At diagnosis

Accumulated

At last visit

cohort

Early

Late

Early

Late

Early

Late

Prednisolone p.o, n (%)

14 (70)

59 (86)

24 (100)

63 (91)

16 (67)

53 (77)

Metylprednisone i.v. n (%)a

0

17 (25)**

2 (8)

22 (32)**

0

1 (1.4)

Any DMARDs, n (%)

1 (4)

35 (51)***

13 (54)

61 (88)***

7 (29)

51 (74)***

 Methotrexate

1 (4)

28 (41)***

11 (46)

55 (80)***

5 (21)

42 (61)***

 Azathioprine

0

7 (10)

7 (29)

18 (26)

2 (8)

8 (12)

 Mycophenelate mofetil

0

 

1 (4)

3 (4)

0

1 (1.4)

 Cyclophosphamideb

2 (8)

6 (9)

4 (17)

7 (15)

0

0

Any biologic, n (%)

0

0

3 (13)

30 (44)*

3 (13)

23 (33)*

 Infliximab

0

0

2 (8)

29 (42)**

1 (4)

16 (23)*

 Etanercept

0

0

2 (8)

3 (4)

1 (4)

1 (1.4)

 Adalimumab

0

0

1 (4)

3 (4)

1 (4)

3 (4)

 Tocilizumab

0

0

1 (4)

5 (7)

0

3 (4)

Other medication, n (%)

      

 Acetylsalicylic acid

2 (8)

32 (46)**

16 (67)

47 (68)

13 (57)

41 (59)

 Statin

1 (4)

16 (23)

16 (67)

34 (49)

13 (57)

32 (46)

  1. The early cohort (n = 24) included all patients diagnosed before year 2000, and the late cohort (n = 63) included patients diagnosed between 2000 and 2012. p.o. oral, i.v. intravenous. aUsually as 1000 mg daily for 3 consecutive days. bGiven as i.v. treatment 6 × 15 mg/kg. Significant differences between the cohorts are indicated: *p < 0.05, **p < 0.01, ***p < 0.001