Fig. 4
From: Ectopic germinal center and megalin defect in primary Sjogren syndrome with renal Fanconi syndrome
Expression of IL-17A and megalin in serial sections. Immunohistochemical staining of IL-17A (a) and megalin (b) on adjacent kidney paraffin sections from a patient with pSS + Fanconi syndrome. Proximal tubules with high expression of IL-17A show loss of megalin (asterisks), and those with preserved megalin expression have no IL-17A staining (arrow). c, d Identification of IL-17A expressing cells (arrow) in renal interstitium with hematoxylin staining of nucleus