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Table 1 Clinical and biological parameters of patients with rheumatoid arthritis

From: Pre-silencing of genes involved in the electron transport chain (ETC) pathway is associated with responsiveness to abatacept in rheumatoid arthritis

  Subset 1 (n = 36) Subset 2 (n = 32)
R (n = 17) NR (n = 19) R (n = 19) NR (n = 13)
0 months 6 months 0 months 6 months 0 months 6 months 0 months 6 months
Age (years) 49.94 +/- 3.63 57.68 +/- 2.67 55.32 +/- 3.02 58.46 +/- 3.32
Sex (F/M), number 17/0* 14/5 15/4 10/3
Disease duration (years) 3.71 +/- 0.86** 10.68 +/- 2.65 5.42 +/- 1.44** 12.85 +/- 3.1
Methotrexate dose (mg/week) 15.29 +/- 1.28 16.58 +/- 3.99 18.03 +/- 3.85 15.58 +/- 3.42
Corticosteroid dose (mg/day) 2.44 +/- 0.77 2.71 +/- 0.75 2.64 +/- 0.8 3.46 +/- 1.14
Tender joint count/28 10.29 +/- 1.48 1.47 +/- 0.5$$$ 14.42 +/- 1.46£££ 6.37 +/- 0.79 11.10 +/- 1.56 1.32 +/- 0.37$$$ 11.46 +/- 2.05 6.92 +/- 1.68£££
Swollen joint count/28 10.24 +/- 1.31 2.59 +/- 0.74$$$ 11.26 +/- 0.92£££ 6.21 +/- 1.10 9.63 +/- 1.15 1.74 +/- 0.49$$$ 10.85 +/- 1.41 5.08 +/- 0.81£££
Patient assessment of disease (VAS scale/100 mm) 58.24 +/- 5.91* 16.29 +/- 4.37$$$ 68.58 +/- 4.28£££ 35.68 +/- 4.85 48.95 +/- 4.83* 19.74 +/- 3.87$$$ 60.62 +/- 5.37 37.08 +/- 5.35£££
DAS28(CRP) 4.98 +/- 0.24** 2.37 +/- 0.13$$$ 5.90 +/- 0.2£££ 4.20 +/- 0.19 4.86 +/- 0.23** 2.41 +/- 0.11$$$ 5.35 +/- 0.25 4.13 +/- 0.27£££
CRP (mg/L) 7.24 +/- 1.42** 2.18 +/- 0.44$$$ 27.69 +/- 6.71££ 12.34 +/- 3.46 8.16 +/- 2.44** 3.56 +/- 0.83$$$ 16.64 +/- 5.39 11.38 +/- 2.46££