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Table 1 Clinical and biological parameters of patients with rheumatoid arthritis

From: Pre-silencing of genes involved in the electron transport chain (ETC) pathway is associated with responsiveness to abatacept in rheumatoid arthritis

 

Subset 1 (n = 36)

Subset 2 (n = 32)

R (n = 17)

NR (n = 19)

R (n = 19)

NR (n = 13)

0 months

6 months

0 months

6 months

0 months

6 months

0 months

6 months

Age (years)

49.94 +/- 3.63

57.68 +/- 2.67

55.32 +/- 3.02

58.46 +/- 3.32

Sex (F/M), number

17/0*

14/5

15/4

10/3

Disease duration (years)

3.71 +/- 0.86**

10.68 +/- 2.65

5.42 +/- 1.44**

12.85 +/- 3.1

Methotrexate dose (mg/week)

15.29 +/- 1.28

16.58 +/- 3.99

18.03 +/- 3.85

15.58 +/- 3.42

Corticosteroid dose (mg/day)

2.44 +/- 0.77

2.71 +/- 0.75

2.64 +/- 0.8

3.46 +/- 1.14

Tender joint count/28

10.29 +/- 1.48

1.47 +/- 0.5$$$

14.42 +/- 1.46£££

6.37 +/- 0.79

11.10 +/- 1.56

1.32 +/- 0.37$$$

11.46 +/- 2.05

6.92 +/- 1.68£££

Swollen joint count/28

10.24 +/- 1.31

2.59 +/- 0.74$$$

11.26 +/- 0.92£££

6.21 +/- 1.10

9.63 +/- 1.15

1.74 +/- 0.49$$$

10.85 +/- 1.41

5.08 +/- 0.81£££

Patient assessment of disease (VAS scale/100 mm)

58.24 +/- 5.91*

16.29 +/- 4.37$$$

68.58 +/- 4.28£££

35.68 +/- 4.85

48.95 +/- 4.83*

19.74 +/- 3.87$$$

60.62 +/- 5.37

37.08 +/- 5.35£££

DAS28(CRP)

4.98 +/- 0.24**

2.37 +/- 0.13$$$

5.90 +/- 0.2£££

4.20 +/- 0.19

4.86 +/- 0.23**

2.41 +/- 0.11$$$

5.35 +/- 0.25

4.13 +/- 0.27£££

CRP (mg/L)

7.24 +/- 1.42**

2.18 +/- 0.44$$$

27.69 +/- 6.71££

12.34 +/- 3.46

8.16 +/- 2.44**

3.56 +/- 0.83$$$

16.64 +/- 5.39

11.38 +/- 2.46££