From: Gout and subsequent erectile dysfunction: a population-based cohort study from England
Variable | Controls | Gout cases | Adjusteda HR | 95% CI | Absolute risk differenceb | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
N | Rateb | 95% CI | N | Rateb | 95% CI | |||||||
Overall | 4124 | 136.2 | 132.1 | 140.4 | 1736 | 192.8 | 184.0 | 202.1 | 1.31 | 1.24 | 1.40 | 56.6 |
Age | ||||||||||||
≤ 34 | 68 | 34.6 | 27.3 | 43.9 | 42 | 61.4 | 45.4 | 83.1 | 1.20 | 0.79 | 1.83 | 26.8 |
35–44 | 548 | 76.2 | 70.1 | 82.8 | 251 | 112.6 | 99.5 | 127.4 | 1.18 | 1.01 | 1.39 | 36.4 |
45–54 | 1551 | 146.0 | 138.9 | 153.5 | 653 | 211.7 | 196.1 | 228.6 | 1.28 | 1.16 | 1.41 | 65.7 |
55–64 | 1957 | 186.3 | 178.3 | 194.8 | 790 | 262.8 | 245.1 | 281.8 | 1.37 | 1.25 | 1.49 | 76.5 |
Smoking status | ||||||||||||
Never/ex-smokers | 3281 | 132.8 | 128.4 | 137.5 | 1487 | 191.2 | 181.7 | 201.1 | 1.32 | 1.24 | 1.41 | 58.3 |
Current smoker | 843 | 151.1 | 141.2 | 161.6 | 249 | 203.2 | 179.5 | 230.1 | 1.29 | 1.11 | 1.50 | 52.2 |
Alcohol consumption | ||||||||||||
Never/ex-drinkers | 834 | 112.3 | 104.9 | 120.2 | 283 | 206.7 | 183.9 | 232.2 | 1.77 | 1.53 | 2.05 | 94.4 |
Current drinkers (1–9 units/week) | 1716 | 132.6 | 126.5 | 139.1 | 601 | 184.2 | 170.1 | 199.5 | 1.29 | 1.17 | 1.42 | 51.6 |
Current drinkers (≥10 units/week) | 1574 | 158.7 | 151.1 | 166.8 | 852 | 194.9 | 182.2 | 208.4 | 1.21 | 1.11 | 1.32 | 36.2 |
Body mass index | ||||||||||||
Normal | 943 | 117.4 | 110.1 | 125.1 | 201 | 157.8 | 137.4 | 181.1 | 1.34 | 1.14 | 1.57 | 40.4 |
Underweight | 18 | 67.5 | 42.5 | 107.2 | - | - | - | - | - | - | - | - |
Overweight | 1659 | 146.5 | 139.6 | 153.7 | 696 | 196.5 | 182.4 | 211.6 | 1.33 | 1.21 | 1.45 | 50.0 |
Obese | 1068 | 170.0 | 160.1 | 180.5 | 712 | 204.2 | 189.7 | 219.7 | 1.23 | 1.11 | 1.35 | 34.1 |
Missing | 436 | 99.6 | 90.7 | 109.4 | 126 | 189.5 | 159.1 | 225.6 | 1.71 | 1.37 | 2.14 | 89.8 |
Comorbidities | ||||||||||||
Congestive heart disease | 443 | 174.2 | 158.7 | 191.2 | 253 | 227.6 | 201.2 | 257.5 | 1.26 | 1.07 | 1.47 | 53.4 |
Diabetes | 946 | 343.6 | 322.4 | 366.2 | 514 | 349.4 | 320.4 | 380.9 | 1.05 | 0.94 | 1.74 | 5.8 |
Hypertension | 1347 | 173.4 | 164.4 | 183.0 | 852 | 206.8 | 193.4 | 221.2 | 1.18 | 1.09 | 1.29 | 33.4 |
Chronic renal disease | 122 | 106.3 | 89.0 | 127.0 | 129 | 149.5 | 125.8 | 177.7 | 1.41 | 1.10 | 1.81 | 43.2 |
Depression | 872 | 168.5 | 157.7 | 180.0 | 381 | 216.1 | 195.4 | 238.9 | 1.26 | 1.11 | 1.43 | 47.6 |